The paper considers the stabilization for systems with interval time-varying delay. By decomposing the delay interval into multiple equidistant subintervals and considering the triple integral terms, a novel Lyapunov-krasovskii functional(LKF) is defined. Then extended integral inequality and convex combination approach are used to estimate the derivative of the constructed functional, and as a result, the new stability criterion with less conservatism and decision variables is obtained. On this basis, the state feedback controller is designed, by using linearization method, the existence condition of controller is obtained in terms of linear matrix inequalities(LMIs), and the specific form of controller is also given, moreover, by selecting the appropriate parameter value, the stabilization time of the system can be reduced. Numerical examples are given to illustrate the effectiveness of the proposed method.
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http://dx.doi.org/10.1016/j.isatra.2017.05.017 | DOI Listing |
J Public Health Manag Pract
November 2024
Author Affiliations: National Association of Chronic Disease Directors, Decatur, Georgia (Dr Lankau, Mss Dudley, Miller, and Shields, Dr Alongi, Ms Macchi, and Dr Hohman); and Public Health Associate Program, Centers for Disease Control and Prevention, Atlanta, Georgia (Ms Chiang).
Objective: The National Association of Chronic Disease Directors (NACDD) is a nonprofit organization that supports state and territorial chronic disease prevention and health promotion efforts through capacity building and technical assistance. Each year, NACDD surveys health department leaders who oversee chronic disease prevention and health promotion (hereafter, Chronic Disease Directors). We have previously used the annual survey results to inform strategic planning and resource allocation but have not historically published key findings in the peer-reviewed literature.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Shenzhen Hospital, Southern Medical University, Shenzhen 518000, China.
ADAR is highly expressed and correlated with poor prognosis in hepatocellular carcinoma (HCC), yet the role of its constitutive isoform ADARp110 in tumorigenesis remains elusive. We investigated the role of ADARp110 in HCC and underlying mechanisms using clinical samples, a hepatocyte-specific knock-in mouse model, and engineered cell lines. ADARp110 is overexpressed and associated with poor survival in both human and mouse HCC.
View Article and Find Full Text PDFAnal Chem
January 2025
The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
CD28 is a costimulatory receptor that provides the second signal necessary for T-cell activation and is associated with diseases, including rheumatoid arthritis, asthma, and cancer. Targeting CD28 is crucial for both functional bioanalysis and therapeutic development. Molecular probes, particularly fluorescent probes, can enhance our understanding of CD28's cellular roles.
View Article and Find Full Text PDFCell Biol Toxicol
January 2025
Department of Radiology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, 110004, Liaoning Province, China.
Thyroid cancer (THCA) is an increasingly common malignant tumor of the endocrine system, with its incidence rising steadily in recent years. For patients who experience recurrence or metastasis, treatment options are relatively limited, and the prognosis is poor. Therefore, exploring new therapeutic strategies has become particularly urgent.
View Article and Find Full Text PDFAppl Microbiol Biotechnol
January 2025
School of Chemical Engineering, Sungkyunkwan University, 2066 Seobu-Ro, Jangan-GuGyeonggi-Do 16419, Suwon-Si, South Korea.
Process intensification and simplification in biopharmaceutical manufacturing have driven the exploration of advanced feeding strategies to improve culture performance and process consistency. Conventional media design strategies, however, are often constrained by the stability and solubility challenges of amino acids, particularly in large-scale applications. As a result, dipeptides have emerged as promising alternatives.
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