Metabolic Engineering Group, Unidad de Genómica Avanzada, Laboratorio Nacional de Genómica para la Biodiversidad (LANGEBIO) del Centro de Investigación y Estudios Avanzados, Km. 9.6 Libramiento Norte Carr. Irapuato-León, 36821 Irapuato, Guanajuato, Mexico. Electronic address:
Published: June 2017
AI Article Synopsis
Article Abstract
Low inorganic phosphate (Pi) availability causes terminal differentiation of the root apical meristem (RAM), a phenomenon known as root meristem exhaustion or determined growth. Here, we report that the CLE14 peptide acts as a key player in this process. Low Pi stress induces iron mobilization in the RAM through the action of LPR1/LPR2, causing expression of CLE14 in the proximal meristem region. CLV2 and PEPR2 receptors perceive CLE14 and trigger RAM differentiation, with concomitant downregulation of SHR/SCR and PIN/AUXIN pathway. Our results reveal multiple steps of the molecular mechanism of one of the most physiologically important root nutrient responses.
Anemia is a common and disabling complication of chronic kidney disease (CKD). Current therapies can be burdensome, and full correction of anemia is limited by cardiovascular side effects. New approaches that may offer additional therapeutic options are needed.
U.S. Environmental Protection Agency, Office of Research and Development, Center for Environmental Solutions and Emergency Response, Andrew W. Breidenbach Research Center, 26 West Marin Luther King Drive, Cincinnati, OH 45268, USA. Electronic address:
The mobility and bioavailability of metal contaminants such as lead (Pb) and zinc (Zn) is impacted by their interactions with other sediment constituents such as iron (Fe), sulfur (S), and organic matter, which depend on sediment redox conditions. Understanding the role that water level fluctuations have on redox conditions and subsequent impacts on metal mobility is critical for predicting impacts of increased wetting and drying cycles resulting from climate-related changes or management actions. This study measured the sediment-porewater partitioning of Pb and Zn in the Coeur d'Alene River basin downstream of the Bunker Hill Superfund Site under both flooded and seasonally dry conditions.
Collaborative Innovation Center of Recovery and Reconstruction of Degraded Ecosystem in Wanjiang Basin Co-founded by Anhui Province and Ministry of Education, School of Ecology and Environment, Anhui Normal University, Wuhu 241002, China; Anhui Provincial Engineering Laboratory of Water and Soil Pollution Control and Remediation, Anhui Normal University, Wuhu 241002, China. Electronic address:
Iron reduction impacts the mobilization and thionation of diphenylarsinic acid (DPAA) in soil, but the contribution of crystalline and non-crystalline iron remains unknown. A paddy soil deficient in non-crystalline iron (P-Fe), crystalline and non-crystalline iron (P-Fe) were incubated with sulfate-plus-lactate, and the results were compared with paddy soil (P) in our previous study. For treatments without ferrous sulfide (FeS) precipitation, the solution-to-solid ratio (R) of DPAA increased slightly and dramatically with iron reduction, respectively, for P-Fe and P, suggesting that the reduction of non-crystalline iron contributes more to DPAA mobilization than crystalline iron.
Banded iron formations (BIFs) are chemical sedimentary rocks commonly utilized for exploring the chemistry and redox state of the Precambrian ocean. Despite their significance, many aspects regarding the crystallization pathways of iron oxides in BIFs remain loosely constrained. In this study, we combine magnetic properties characterization with high-resolution optical and electron imaging of finely laminated BIFs from the 2.
Vitamin A deficiency (VAD) and iron deficiency anemia coexist around the world, particularly in children and women of reproductive age in low- and middle-income countries. Within this scenario, there is a known interaction between vitamin A and iron, and it has been postulated that lack of vitamin A impairs iron metabolism, leading to vitamin A deficiency anemia (VADA). Current animal, epidemiological, and clinical studies support this notion.
