AI Article Synopsis
- - Sclerema neonatorum is a type of panniculitis that causes hardening of the subcutaneous tissue in primarily ill and preterm newborns, showing little inflammation.
- - The prognosis is often poor despite various treatment options, which include antibiotics, immunoglobulins, steroids, and exchange transfusions.
- - The case presented involves a successful treatment of a one-week-old preterm baby with sclerema neonatorum using parenteral steroids and antibiotics, highlighting the potential lifesaving role of steroids, particularly in resource-limited settings.
Article Abstract
Sclerema neonatorum is a form of panniculitides characterized by diffuse hardening of subcutaneous tissue with minimal inflammation. It usually affects ill and preterm neonates. Prognosis is usually poor in many cases despite aggressive management. Various treatment modalities (antibiotics, intravenous immunoglobulin, steroids, and exchange transfusion) have been explained in literature. Steroids due to its easy availability and low cost can prove to be lifesaving in such cases, especially in resource poor countries. Here, we report a case of sclerema neonatorum in a one-week preterm baby treated successfully with parenteral steroids and antibiotics.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444035 | PMC |
| http://dx.doi.org/10.1155/2017/4836142 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Article Synopsis
- Sclerema neonatorum (SN) is a serious and rare skin condition found in newborns, characterized by the hardening of skin and fat tissue, primarily affecting sick, premature infants.
- The condition typically appears within the first week of life and is diagnosed clinically, with symptoms sparing areas without fat like palms and soles.
- In a case study, an eight-day-old premature infant with early-onset sepsis showed signs of SN but, despite treatment with antibiotics and topical creams, sadly passed away by day twelve.
Risk Factors for Mortality in Neonatal Gastric Perforation: A Retrospective Cohort Study.
Front Pediatr
May 2021
Department of Neonatal Surgery, Children's Hospital of Chongqing Medical University, Chongqing, China.
Article Synopsis
- * The study employed a retrospective analysis of patient data from a pediatric hospital and identified three main factors associated with increased mortality risk: shock, elevated serum lactic acid levels, and low platelet counts.
- * Further analysis showed that certain predictors of death varied between pre-term and term infants, with serum lactic acid levels and platelet counts being particularly significant in both groups, indicating the need for targeted clinical attention in these vulnerable populations.
Sclerema Neonatorum in a Term Infant: A Case Report and Literature Review.
Case Rep Pediatr
December 2020
Department of Surgery, Faculty of Clinical Medicine and Dentistry, Kampala International University, Kampala, Uganda.
Article Synopsis
- Sclerema neonatorum (SN) is a rare skin condition that mainly affects preterm infants, particularly those with other health issues, and usually appears within the first week of life.
- The condition is characterized by hardening of the skin and subcutaneous tissues, primarily starting in areas like the buttocks and thighs, and can lead to serious complications with a high risk of mortality even with treatment.
- The case report discusses a newborn with typical signs and histopathological features of SN, highlighting its severity and the challenges in managing this condition.
[Not Available].
Dermatol Online J
November 2020
Servicio de Dermatología, Hospital Clínico Universitario, Valencia.
Article Synopsis
- Subcutaneous fat necrosis of the newborn is a rare condition that occurs mainly in full-term or post-term infants, often linked to complications during childbirth or maternal health issues.
- The skin shows red, swollen plaques and nodules usually on the back and shoulders, and diagnosis relies on clinical observation and pathology tests that reveal specific inflammatory changes and fat cell necrosis.
- While generally self-limiting, it can lead to serious complications like hypercalcemia, requiring careful monitoring and treatment during diagnosis and follow-up.
Efficacy of vitamin E combined with heparin sodium cream in treatment of scleredema neonatorum.
Panminerva Med
June 2021
Department of Pediatrics -
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!