Relationships between lung cancer incidences and air pollutants.

Technol Health Care

Department of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.

Published: July 2017

Background: Statistics on lung cancer incidences and air pollutants show a strong correlation between air pollutant concentrations and pulmonary diseases. And environmental effects on lung cancer incidences remain highly unknown and uncertain in China.

Objective: This study aims to measure the relationships between different air pollutants and lung cancer incidences in Tianjin.

Methods: One thusand five hundred patients across 27 districts in Tianjin were studied for lung cancer incidences. The patients had come into contact with various air pollutants such as PM2.5, PM10, SO2, NO2, CO, and O3. These pollutants were measured daily and were published via a Geographic Information System across the 27 districts of Tianjin. The air pollutant compositions of environments the patients lived in were determined using the nearest air monitoring station to the patient. And we used rough set theory to measure the relationships between different air pollutants and lung cancer incidences.

Results: Different air pollutants and combinations of pollutants impacted lung cancer incidences differently across different districts, sexes, and lung cancer types in Tianjin.

Conclusions: Based on data analysis and interpretation, rough set theory provided data relationships that were objective and interpretable. The method is simple, general, and efficient, and lays the foundation for further applications in other cities.

Download full-text PDF

Source
http://dx.doi.org/10.3233/THC-171344DOI Listing

Publication Analysis

Top Keywords

lung cancer
32
cancer incidences
24
air pollutants
24
air
9
cancer
8
incidences air
8
pollutants
8
air pollutant
8
measure relationships
8
relationships air
8

Similar Publications

Progress report on multiple endocrine neoplasia type 1.

Fam Cancer

January 2025

Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Multiple endocrine neoplasia type 1 (MEN1) syndrome is an autosomal dominant disorder caused by a germline pathogenic variant in the MEN1 tumor suppressor gene. Patients with MEN1 have a high risk for primary hyperparathyroidism (PHPT) with a penetrance of nearly 100%, pituitary adenomas (PitAd) in 40% of patients, and neuroendocrine neoplasms (NEN) of the pancreas (40% of patients), duodenum, lung, and thymus. Increased MEN1-related mortality is mainly related to duodenal-pancreatic and thymic NEN.

View Article and Find Full Text PDF

Design, synthesis, and in vitro antitumor evaluation of novel benzimidazole acylhydrazone derivatives.

Mol Divers

January 2025

State Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for R&D of Fine Chemicals of Guizhou University, Guiyang, Guizhou, 550025, People's Republic of China.

This study focuses on the design, synthesis, and evaluation of benzimidazole derivatives for their anti-tumor activity against A549 and PC-3 cells. Initial screening using the MTT assay identified compound 5m as the most potent inhibitor of A549 cells with an IC of 7.19 μM, which was superior to the positive agents 5-Fluorouracil and Gefitinib.

View Article and Find Full Text PDF

Background: Pre-cancer onset of cachexia raises uncertainties regarding the optimal timing for early intervention in lung cancer patients. We aimed to examine changes in physical function, nutritional status, and cachexia incidence in patients with lung cancer from the initial visit to treatment initiation and determine the effect of these changes on lung cancer treatment.

Methods: This single-center retrospective cohort study enrolled patients suspected of having advanced lung cancer who visited Kansai Medical University Hospital between January and February 2023 and were definitely diagnosed with the disease.

View Article and Find Full Text PDF

Circulating Tumor DNA Detection for Recurrence Monitoring of Stage I Non-Small Cell Lung Cancer Treated With Microwave Ablation.

Thorac Cancer

January 2025

Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.

Purpose: As microwave ablation continues to be used in patients with inoperable stage I non-small cell lung cancer (NSCLC), it is particularly important to monitor efficacy. Whether plasma ctDNA detection can predict its efficacy should be illustrated.

Methods: We recruited 43 patients with inoperative stage I NSCLC, all of whom underwent biopsy-synchronous microwave ablation (MWA).

View Article and Find Full Text PDF

Long-term use of low-dose aspirin has been demonstrated to reduce cancer risk, but the duration of necessary medication use remains uncertain. This study aimed to investigate the long-term chemoprotective effect of aspirin among the Chinese population. This population-based study included all aspirin users between 2000 and 2019.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!