Introduction: Inadvertent perioperative hypothermia occurs frequently during elective caesarean section but perioperative active body warming is not widely used. There is a paucity of evidence of its use in the obstetric population, and no applicable guidelines. We set out to identify a superior active warming method for preventing inadvertent perioperative hypothermia.
Methods: Following ethical approval, 132 women presenting for uncomplicated elective caesarean section under spinal anaesthesia were recruited. All participants received in-line intravenous fluid warming and were randomised to one of three parallel groups: no active body warming; forced air warming; and conduction mattress warming. The primary outcome was the difference in mean core temperature, measured on admission to the recovery room, between study groups. Core temperature and thermal comfort were measured perioperatively at 15-min intervals. Estimated blood loss, haemoglobin change, length of hospital stay and neonatal core temperature were also recorded.
Results: One-hundred-and-thirty-one women completed the study. There was no significant difference in mean core temperature on admission to the recovery room (36.6°C vs. 36.6°C vs. 36.6°C, η=0.005, P=0.74). Maternal hypothermia was prevented in all groups with only 0.3% hypothermic at any of the temperature measurements (3/1016). There was no difference in mean neonatal core temperature (36.3°C vs. 36.3°C vs. 36.3°C, η=0.003, P=0.82); however, 59.4% (76/128) of all neonates were hypothermic.
Conclusion: In-line intravenous fluid warming is sufficient to prevent maternal hypothermia and maintain core temperature. The addition of active body warming conferred no added benefit.
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http://dx.doi.org/10.1016/j.ijoa.2017.04.008 | DOI Listing |
Cell Stress
December 2024
Growth Factors, Nutrients and Cancer Group, Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO) Madrid, ES28029 Spain.
Cold exposure has been historically used for medicinal purposes, but its benefits and associated mechanisms in mammalian organisms still remain unclear. Here, we explore the chemoprotective properties of cold temperature using a mouse model of hepatocellular carcinoma (HCC) that recapitulates several human features. Chronic cold exposure is shown to prolong lifespan in diseased mice, enhance liver health, and suppress the development of aggressive HCC, preventing hepatocellular hypertrophy, high-grade oval cell hyperplasia, liver steatosis, and aberrant hepatocyte hyperproliferation.
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January 2025
Consiglio Nazionale delle Ricerche (CNR) - Istituto per la Sintesi Organica e la Fotoreattività (ISOF), via Piero Gobetti 101, 40129 Bologna, Italy.
This study reveals the capability of nanostructured organic materials to undergo pseudomorphic transformations, a ubiquitous phenomenon occurring in the mineral kingdom that involves the replacement of a mineral phase with a new one while retaining the original shape and volume. Specifically, it is demonstrated that the postoxidation process induced by HOF·CHCN on preformed thiophene-based 1D nanostructures preserves their macro/microscopic morphology while remarkably altering their electro-optical properties by forming a new oxygenated phase. Experimental evidence proves that this transformation proceeds via an interface-coupled dissolution-precipitation mechanism, leading to the growth of a porous oxidized shell that varies in thickness with exposure time, enveloping the pristine smooth core.
View Article and Find Full Text PDFSci Rep
January 2025
Key Laboratory for Information System of Mountainous Area and Protection of Ecological Environment of Guizhou Province, Guizhou Normal University, Guian, 550025, China.
Removal of accumulated dyes from the environment water bodies is essential to prevent further harm to humans. The development and design of new alternative nanoadsorbents that can conveniently, quickly, and efficiently improve the adsorption and removal efficiency of dyes from wastewater remains a huge challenge. An amorphous TiO with a magnetic core-shell-shell structure (FeO@PDA@a-TiO, denoted as FPaT) was constructed through a series of steps.
View Article and Find Full Text PDFJ Sci Med Sport
December 2024
Korey Stringer Institute, Department of Kinesiology, University of Connecticut, United States of America.
Prehospital management of exertional heat stroke (EHS) consists of monitoring rectal temperature (T) while aggressively cooling via cold water immersion. Recent recommendations suggest using central nervous system (CNS) dysfunction to determine cessation of cooling when T is not available. We examined cognitive responses of two runners with EHS after a road race.
View Article and Find Full Text PDFBiosystems
January 2025
Lomonosov Moscow State University, Moscow, Russian Federation. Electronic address:
As an important part of lipid metabolism the liver produces large particles called very low density lipoproteins, filled mostly with triglyceride and cholesterol esters mixture. A large percentage of the mixture composition components has a melting point above physiological temperature. Thus solid cluster formation or phase transition could be expected.
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