Optimization of the dosimetric leaf gap for use in planning VMAT treatments of spine SABR cases.

J Appl Clin Med Phys

Genesis Cancer Care Queensland, Wesley Medical Centre, Suite 1 40 Chasely St, Auchenflower, Qld, 4066, Australia.

Published: July 2017

The dosimetric leaf gap (DLG) is a beam configuration parameter used in the Varian Eclipse treatment planning system, to model the effects of rounded MLC leaf ends. Measuring the DLG using the conventional sliding-slit technique has been shown to be produce questionable results for some volumetric modulated arc therapy (VMAT) treatments. This study therefore investigated the use of radiochromic film measurements to optimize the DLG specifically for the purpose of producing accurate VMAT plans using a flattening-filter-free (FFF) beam, for use in treating vertebral targets using a stereotactic (SABR, also known as SBRT) fractionation schedule. Four test treatments were planned using a VMAT technique, to deliver a prescription of 24 Gy in 3 fractions to four different spine SABR treatment sites. Measurements of the doses delivered by these treatments were acquired using an ionization chamber and radiographic film. These measurements were compared with the doses calculated by the treatment planning system using a range of DLG values, including a DLG identified using the conventional sliding-slit method (1.1 mm). An optimal DLG value was identified, as the value that produced the closest agreement between the planned and measured doses (1.9 mm). The accuracy of the dose calculations produced using the optimized DLG value was verified using additional radiochromic film measurements in a heterogeneous phantom. This study provided a specific initial DLG (1.9 mm) as well as a film-based optimization method, which may be used by radiotherapy centers when attempting to commission or improve an FFF VMAT-based SABR treatment programme.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874863PMC
http://dx.doi.org/10.1002/acm2.12106DOI Listing

Publication Analysis

Top Keywords

film measurements
12
dosimetric leaf
8
leaf gap
8
vmat treatments
8
spine sabr
8
dlg
8
treatment planning
8
planning system
8
conventional sliding-slit
8
radiochromic film
8

Similar Publications

During maritime operations, extreme events such as explosions, grounding, and seal failures can cause water ingress into lubricant compartments, forming oil-water emulsions that significantly affect the lubrication performance of ship stern bearings. Existing studies mainly focus on low water content, with limited exploration of the impact of high water content on lubrication performance. To address this gap, viscosity measurements of oil-water mixtures were conducted, and an emulsification viscosity equation applicable to varying water contents was derived.

View Article and Find Full Text PDF

Physical and photophysical properties of starch-based biopolymer films containing 5-(4-nitrophenyl)-1,3,4-thiadiazol-2-amine (NTA) powder as a nanofiller were examined using atomic force microscopy (AFM), Fourier-transform infrared spectroscopy (FTIR), stationary UV-Vis and fluorescence spectroscopy as well as resonance light scattering (RLS) and time-resolved measurements, and where possible, analyzed with reference to pristine NTA solutions. AFM studies revealed that the addition of NTA into the starch biopolymer did not significantly affect surface roughness, with all examined films displaying similar Sq values ranging from 70.7 nm to 79.

View Article and Find Full Text PDF

Topological semimetals have recently garnered widespread interest in the quantum materials research community due to their symmetry-protected surface states with dissipationless transport which have potential applications in next-generation low-power electronic devices. One such material, [Formula: see text], exhibits Dirac nodal arcs and although the topological properties of single crystals have been investigated, there have been no reports in crystalline thin film geometry. We examined the growth of [Formula: see text] heterostructures on a range of single crystals by optimizing the electron beam evaporation of Pt and Sn and studied the effect of vacuum thermal annealing on phase and crystallinity.

View Article and Find Full Text PDF

Studies on Morphological Evolution of Gravure-Printed ZnO Thin Films Induced by Low-Temperature Vapor Post-Treatment.

Nanomaterials (Basel)

December 2024

Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Portici Research Centre, P.le E. Fermi 1, Portici, 80055 Naples, Italy.

In recent years, the morphology control of semiconductor nanomaterials has been attracting increasing attention toward maximizing their functional properties and reaching their end use in real-world devices. However, the development of easy and cost-effective methods for preparing large-scale patterned semiconductor structures on flexible temperature-sensitive substrates remains ever in demand. In this study, vapor post-treatment (VPT) is investigated as a potential, simple and low-cost post-preparative method to morphologically modify gravure-printed zinc oxide (ZnO) nanoparticulate thin films at low temperatures.

View Article and Find Full Text PDF

(AlCrMoNiTi)N high-entropy alloy nitride (HEAN) films were synthesized at various bias voltages using the co-filter cathodic vacuum arc (co-FCVA) deposition technique. This study systematically investigates the effect of bias voltage on the microstructure and performance of HEAN films. The results indicate that an increase in bias voltage enhances the energy of ions while concomitantly reducing the deposition rate.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!