ANTIOXIDANT ACTIVITY AND A-AMYLASE INHIBITORY POTENTIAL OF L.

Afr J Tradit Complement Altern Med

Research Unit on Nutrition, Regulation of Metabolic Systems and Atherosclerosis, High School of Sciences and Technology of Health of Tunis, 176 Bab Souika, BP1006, Tunis, Tunisia.

Published: August 2017

Background: Diabetes mellitus is one of the most common endocrinal disorders and medicinal plants continue to play an important role in the management of this disease. In this study, was investigated for the antioxidant and α-amylase inhibition activities.

Materials And Methods: Methanolic extract of was investigated for its potential antioxidant activity. The extracts' total phenolic and flavonoid contents and scavenging capacity for free radicals were evaluated. The α-amylase inhibition assay was also carried.

Results: extract exhibits a total Phenolic and flavonoid levels respectively (21.918 mg GAE/g and 2.647mg ER/g). The free radical scavenging activity was found to be prominent against DPPH with an IC50 of 0.668 mg/ml and against ABTS with an IC50 of 0.467 mg/ml. Extract showed a significant ferric ion reducing activities with an IC50 of4.962 mg/ml.

Conclusion: exerted a higher inhibitory activity against α-amylase. The obtained results support the antidiabetic use of .

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446433PMC
http://dx.doi.org/10.21010/ajtcam.v14i2.1DOI Listing

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