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Using Inhibitory Learning Theories to Optimise Treatment for Children with Anxiety Disorders.
Curr Top Behav Neurosci
January 2025
Black Dog Institute, University of New South Wales, Sydney, Australia.
Anxiety disorders in children lead to substantial impairment in functioning and development. Even the most effective gold standard treatments for childhood anxiety have 50% remission rates, suggesting a critical need to improve current treatments. Optimising exposure, the key component of anxiety treatments, represents a promising way to do so.
View Article and Find Full Text PDFObjective: To investigate young people's experience of retainer wear in the immediate term and at 6 months after appliance removal, and to explore the factors affecting retainer wear adherence.
Design: Qualitative study.
Setting: Orthodontic departments at two teaching hospitals in Yorkshire, UK.
Spatially Resolved Multiomics: Data Analysis from Monoomics to Multiomics.
BME Front
January 2024
CAS Key Lab of Bio-Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China.
Spatial monoomics has been recognized as a powerful tool for exploring life sciences. Recently, spatial multiomics has advanced considerably, which could contribute to clarifying many biological issues. Spatial monoomics techniques in epigenomics, genomics, transcriptomics, proteomics, and metabolomics can enhance our understanding of biological functions and cellular identities by simultaneously measuring tissue structures and biomolecule levels.
View Article and Find Full Text PDFAn exploratory qualitative assessment of patient and clinician perspectives on patient-reported outcome measures and disease-modifying therapies in adults with spinal muscular atrophy.
J Rehabil Med
January 2025
Stan Cassidy Centre for Rehabilitation, Horizon Health Network, Fredericton, New Brunswick, Canada; Dalhousie Medicine New Brunswick, Dalhousie University, Saint John, New Brunswick, Canada.
Objective: To understand patient, caregiver, and clinician perspectives on patient-reported outcome measures, critical functional domains, and disease-modifying therapies in adult spinal muscular atrophy.
Design: An exploratory qualitative single-site study.
Patients: Ten adults with spinal muscular atrophy and two clinicians participated in semi-structured interviews.
Communicating neurological prognosis in the prenatal period: a narrative review and practice guidelines.
Pediatr Res
January 2025
Division of Neurology, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Clinicians may face an array of challenges in conducting fetal neurological consultations including prognostic uncertainty, a lack of training in fetal counseling, and limited opportunity to build rapport with families. In this setting, it is critical to employ high-quality, family-centered care to allow expectant parents to make informed decisions. Despite the challenges and gravity of these consultations, there remains limited data outlining best conduct and communication practices.
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