The term Mycoplasma pneumoniae-induced rash and mucositis (MIRM) was recently proposed to identify the mucocutaneous condition secondary to M. pneumoniae infection that had historically been regarded among the more confusing pathologies of erythema multiforme and Stevens-Johnson syndrome. Based on a number of previous reports, these syndromes require differentiation since they have different prognoses and specific treatment requirements. We report a case of oral and genital erosions that strongly resembled MIRM without rash but were found to be secondary to a Chlamydia pneumoniae infection. After a thorough review of the literature on this subject, we propose that C. pneumoniae should also be considered a potential causative agent of MIRM and that this term should be amended to include C. pneumoniae infection.
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http://dx.doi.org/10.1111/pde.13140 | DOI Listing |
BMC Infect Dis
January 2025
Department of Radiology, The Affiliated Brain Hospital of Nanjing Medical University, No.264, Guangzhou Road, Gulou District, Nanjing, 210029, Jiangsu, China.
Purpose: To present the different findings of Chlamydia psittaci (C. psittaci) pneumonia on computed tomography (CT) according to the progression of the disease, to improve diagnostic accuracy, guide early clinical diagnosis, evaluate treatment efficacy, and reduce the mortality associated with the disease.
Methods: In total, 80 cases of C.
Med J Armed Forces India
December 2024
Associate Professor (Obst & Gynae), Military Hospital Roorkee, India.
Background: In India, the prevalence of Chlamydia Trachomatis (CT) studies in different groups are focused on high-risk populations - HIV-positive women and female sex workers - and have shown a variable prevalence rate ranging from 1.1 to 45%. One concern about comparing these studies is that the enzyme-linked immunosorbent assay (ELISA) test is estimated to be only 65-70% sensitive.
View Article and Find Full Text PDFVaccine
December 2024
Infectious Disease Immunology, Center for Vaccine Research, SSI, Copenhagen, Denmark. Electronic address:
Mucosal secretory IgA (SIgA) produced by subepithelial plasma cells in the lamina propria is the major antigen-specific defense mechanism against mucosal infections. We investigated if a retinoic acid (RA)-containing adjuvant in parenteral immunization, can induce vaccine-specific SIgA in the jejunal lumen in a dose-dependent manner in neonatal pigs immunized with a Chlamydia hybrid antigen. To accurately quantify SIgA responses in mucosal secretions, an antigen-specific ELISA method with secondary detection of porcine secretory component rather than IgA was developed.
View Article and Find Full Text PDFBMJ Open
December 2024
Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.
Introduction: Trachoma is caused by the bacterium (). The WHO recommends the SAFE strategy for trachoma elimination: Surgery for trichiasis, Antibiotics, Facial cleanliness and Environmental improvement. Multiple rounds of SAFE implementation have proven insufficient to eliminate trachoma in Ethiopia, where over 50% of the global trachoma burden remains.
View Article and Find Full Text PDFPublic Health Res (Southampt)
September 2024
Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, UK.
Background: Sex workers' risk of violence and ill-health is shaped by their work environments, community and structural factors, including criminalisation.
Aim: We evaluated the impact of removing police enforcement on sex workers' safety, health and access to services.
Design: Mixed-methods participatory study comprising qualitative research, a prospective cohort study, mathematical modelling and routine data collation.
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