The aim of this study was to determine if the results of activities performed using specially developed serious games for physical rehabilitation could be used as an indicator of the natural maturation and decline of motor control in healthy participants. Eighty-one participants (19 children (5-15 years old), 40 adults (18-65 years old) and 22 aged subjects (60-88 years old) participated in this study. Motions performed were recorded using the Kinect sensor. Three different exercises embedded in the games were used to assess upper limb, trunk and lower limb control. The trial duration and accuracy, measures of gross motor function and fine motor control, respectively, were computed for each participant. ANOVA tests shows statistically significant differences between the three groups for duration (53±15, 27±10 and 119±30s for children, adults and elderly subjects respectively) and accuracy (87±5, 89±10 and 70±8% for children, adults and elderly subjects respectively). The slopes of the curves that approximated the evolution of the performance over various ages are coherent with previous studies about motor control development and physiological decline. The proposed solution, i.e. serious games rehabilitation exercises coupled to motion analysis, seems to be an interesting tool to assess global motor function. Further studies are needed to study the influence of pathologies on the studied parameters.
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http://dx.doi.org/10.1016/j.gaitpost.2017.05.025 | DOI Listing |
Brain Res
January 2025
epartment of Basic Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, China; Key Laboratory of Novel Targets and Drug Study for Neural Repair of Zhejiang Province, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang 310015, China. Electronic address:
Whisker deprivation at different stages of early development results in varied behavioral outcomes. However, there is a notable lack of systematic studies evaluating the specific effects of whisker deprivation from postnatal day 0 (P0) to P14 on adolescent behavioral performance in mice. To investigate these effects, C57BL/6J mice underwent whisker deprivation from P0 to P14 and were subsequently assessed at 5 weeks of age using a battery of tests: motor skills were evaluated using open field test; emotional behavior was evaluated using a series of anxiety- and depression-related behavioral tests; cognitive function was examined via novel location and object recognition tests; and social interactions were analyzed using three-chamber social interaction test.
View Article and Find Full Text PDFSLAS Technol
January 2025
Faculty of Medicine, Jingchu Institute of Technology, Jingmen 448000, Hubei, China. Electronic address:
Mild cognitive impairment (MCI) is an intermediate state between normal aging and dementia, and its symptoms include easy forgetting, distraction, and mental deterioration. This directly affects the patient's motor function, daily living ability, and social adaptability, and brings many difficulties to the patient's reintegration into society. Therefore, clinical research on MCI is very necessary.
View Article and Find Full Text PDFNeuroimage
January 2025
Movement & Neuroscience, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.
When engaged in dynamic or continuous movements, action initiation involves modifying an ongoing motor program rather than initiating it from rest. Event-related theta synchronization over sensorimotor areas is a neurophysiological marker for modifying motor programs. We used electroencephalography (EEG) to examine how task complexity and age affect event-related synchronization (ERS) in the theta band during a dynamic bimanual, visuomotor pinch force task.
View Article and Find Full Text PDFMol Metab
January 2025
Department of Biological Chemistry, University of California, Irvine School of Medicine. Electronic address:
Objectives: Many cancer cells depend on exogenous methionine for proliferation, whereas non-tumorigenic cells can divide in media supplemented with the metabolic precursor homocysteine. This phenomenon is known as methionine dependence of cancer or methionine addiction. The underlying mechanisms driving this cancer-specific metabolic addiction are poorly understood.
View Article and Find Full Text PDFJ Biomech
January 2025
Laboratoire de Simulation et Modélisation du Mouvement, Université de Montréal, Montréal, QC, Canada. Electronic address:
In trampolining, optimizing body orientation during landing reduces injury risk and enhances performance. As trampolinists are subject to motor variability, anticipatory inflight corrections are necessary to regulate their body orientation before landing. We investigated the evolution of a) body orientation and b) limb position (i.
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