AI Article Synopsis

  • Penicillin desensitization is crucial for pregnant patients with severe penicillin allergies who also have syphilis.
  • A pregnant patient with secondary syphilis experienced anaphylaxis during the desensitization process but was successfully treated with intramuscular epinephrine.
  • Continuous fetal monitoring during the episode indicated that the fetus experienced stable conditions, suggesting that epinephrine has little to no immediate negative effects on the fetus in such situations.

Article Abstract

Penicillin desensitization is indicated in pregnant patients with severe allergies to penicillin with syphilis. The immediate effects of intramuscular epinephrine on the fetus during desensitization remain unreported. We describe a pregnant patient with secondary syphilis and penicillin allergy who developed anaphylaxis during penicillin desensitization. Anaphylaxis resolved after administration of intramuscular epinephrine. Throughout the procedure, continuous electronic fetal monitoring showed a stable fetus without a decrease in variability, tachycardia, decelerations, or signs of fetal distress. This case showed that intramuscular epinephrine is effective in treatment of anaphylaxis in a pregnant patient with little to no immediate effects on the fetus.

Download full-text PDF

Source
http://dx.doi.org/10.1080/14767058.2017.1336221DOI Listing

Publication Analysis

Top Keywords

intramuscular epinephrine
16
penicillin desensitization
12
secondary syphilis
8
syphilis penicillin
8
pregnant patient
8
penicillin
5
fetal response
4
intramuscular
4
response intramuscular
4
epinephrine
4

Similar Publications

Anaphylaxis.

Allergy Asthma Clin Immunol

December 2024

Division of Allergy & Immunology, Department of Medicine, Queen's University, Kingston, ON, Canada.

Anaphylaxis is an acute, potentially fatal systemic hypersensitivity reaction with varied mechanisms and clinical presentations. Although prompt recognition and treatment of anaphylaxis are imperative, both patients and healthcare professionals often fail to recognize and diagnose its early signs. Clinical manifestations vary widely, however, the most common signs are cutaneous symptoms, including urticaria and angioedema.

View Article and Find Full Text PDF

A health economic analysis of noninjectable epinephrine compared with intramuscular epinephrine.

Ann Allergy Asthma Immunol

December 2024

Section of Allergy and Immunology, Department of Pediatrics, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.

Background: Noninjectable epinephrine to treat allergic reactions addresses an unmet need. Intranasal epinephrine is approved and a sublingual form is under development. Inhaled epinephrine is poorly studied for anaphylaxis.

View Article and Find Full Text PDF
Article Synopsis
  • Anaphylactic shock is a serious condition triggered by allergens, but there is a general lack of awareness about its risks and management, particularly in the western region of Saudi Arabia.
  • A survey conducted from January to June 2024 involved 501 participants, revealing that while many recognize the danger of anaphylaxis, knowledge about its symptoms and treatment options, such as epinephrine, is low.
  • The results underscore the necessity for public awareness campaigns aimed at improving understanding and preparedness for anaphylactic emergencies.
View Article and Find Full Text PDF
Article Synopsis
  • Alpha-gal syndrome is triggered by tick bites, leading to IgE responses against alpha-gal, a carbohydrate present in mammalian meat, causing delayed allergic reactions 2 to 6 hours after eating.
  • Symptoms can include skin rashes, gastrointestinal issues, and occasionally severe anaphylaxis, often starting near the previous tick bite site.
  • Diagnosis involves monitoring symptom timing and prior tick bite history, with treatment focusing on immediate care during allergic reactions and long-term management requiring a strict meat-free diet.
View Article and Find Full Text PDF

Adverse reactions to radiological contrast media: Prevention and treatment.

Radiologia (Engl Ed)

October 2024

Servicio de Alergia, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa (IIS-P), Madrid, Spain. Electronic address:

Radiological contrast media, both iodinated and gadolinium-based, can lead to adverse reactions. Type A reactions are related to the pharmacological characteristics of the contrast, including side, secondary and toxic effects. Post-contrast acute kidney injury is the most frequent adverse reaction to iodinated contrast media.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!