The problem of maladaptive cultural traits is explored through the notion of adaptive psychological mechanisms. It is suggested that the theory of a specific conformity mechanism is plausible, supported by multidisciplinary data, and helpful in explaining the proliferation and persistence of human maladaptive behavior. © 1996 Wiley-Liss, Inc.
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http://dx.doi.org/10.1002/(SICI)1520-6300(1996)8:5<615::AID-AJHB7>3.0.CO;2-U | DOI Listing |
NPJ Precis Oncol
January 2025
Department of Thoracic Surgery, Peking University People's Hospital, Beijing, 100044, China.
Next-generation sequencing (NGS) offers a promising approach for differentiating multiple primary lung cancers (MPLC) from intrapulmonary metastasis (IPM), though panel selection and clonal interpretation remain challenging. Whole-exome sequencing (WES) data from 80 lung cancer samples were utilized to simulate MPLC and IPM, with various sequenced panels constructed through gene subsampling. Two clonal interpretation approaches primarily applied in clinical practice, MoleA (based on shared mutation comparison) and MoleB (based on probability calculation), were subsequently evaluated.
View Article and Find Full Text PDFStructure
January 2025
Małopolska Centre of Biotechnology, Jagiellonian University, Kraków, Poland. Electronic address:
Deoxyhypusination is the first rate-limiting step of the unique post-translational modification-hypusination-that is catalyzed by deoxyhypusine synthase (DHS) and deoxyhypusine hydroxylase (DOHH). This modification is essential for the activation of translation factor 5A in eukaryotes (eIF5A) and Archaea (aIF5A). This perspective focuses on the structural biology of deoxyhypusination complexes in eukaryotic and archaeal organisms.
View Article and Find Full Text PDFEnviron Pollut
January 2025
College of Oceanology and Food Science, Quanzhou Normal University, Quanzhou 362000, China. Electronic address:
As a crucial source of potable water, the quality of water in Shanmei reservoir strongly and directly impacts the safety and well-being of downstream residents. Microorganisms play a pivotal role in the reservoir's resource and energy cycle. However, ecological protection efforts for the Shanmei reservoir have encountered numerous challenges in recent years.
View Article and Find Full Text PDFPLoS Pathog
January 2025
REHABS, International Research Laboratory, CNRS-NMU-UCBL, George Campus, Nelson Mandela University, George, South Africa.
Plasmodium vivax is the predominant malaria parasite in Latin America. Its colonization history in the region is rich and complex, and is still highly debated, especially about its origin(s). Our study employed cutting-edge population genomic techniques to analyze whole genome variation from 620 P.
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