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Infective endocarditis caused by - a retrospective registry-based study.
Infect Dis (Lond)
January 2025
Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Purpose: Infective endocarditis (IE) is diagnosed using the Duke criteria, which were updated in 2023. In the Duke-ISCVID 2023 criteria, was recognised as a typical IE pathogen. This study investigates the impact of this change and compares the clinical characteristics of IE to IE caused by other pathogens.
View Article and Find Full Text PDFNovel antimicrobial defensin peptides from different coleopteran insects (Coleoptera: Insecta): identification, characterisation and antimicrobial properties.
J Asian Nat Prod Res
January 2025
Department of Molecular Biology and Genetics, Faculty of Science, Sivas Cumhuriyet University, Sivas, Turkey.
Antimicrobial peptides are crucial components of the immune systems of both vertebrates and invertebrates. Here, defensins, the most studied class of antimicrobial molecules in arthropods were investigated in four coleopteran insect species: (DeGeer, 1774), (Linnaeus, 1767), (Linnaeus, 1758), and (Brullé, 1832). The peptides synthesized with over 95% purity and their antimicrobial activities were evaluated by MIC test method.
View Article and Find Full Text PDFSevere palmoplantar keratoderma: a cutaneous complication from sub-optimally controlled type 2 diabetes.
Endocrinol Diabetes Metab Case Rep
January 2025
Summary: Palmoplantar keratoderma (PPK), characterised by excessive epidermal thickening of the skin on the palms and/or plantar surfaces of the feet, can be hereditary or acquired. Here, we report a case of a 53-year-old woman with a history of sub-optimally controlled diabetes mellitus presenting with fevers and decreased Glasgow Coma Scale (GCS) to a tertiary hospital. She was diagnosed with diabetic ketoacidosis (DKA), with blood glucose at 40 mmol/L and ketones at 7 mmol/L, in the setting of a methicillin-sensitive Staphylococcus aureus necrotising soft tissue back infection.
View Article and Find Full Text PDFOmics-based Identification of the Broader Effects of 2-hydroxyisoflavanone Synthase Gene Editing on a Gene Regulatory Network Beyond Isoflavonoid Loss in Soybean Hairy Roots.
Plant Cell Physiol
December 2024
RIKEN Center for Sustainable Resource Science, Yokohama 230-0045, Japan.
Soybean (Glycine max) is a leguminous crop cultivated worldwide that accumulates high levels of isoflavones. Although previous research has often focused on increasing the soybean isoflavone content because of the estrogen-like activity of dietary soy in humans, the rapidly increasing demand for soybean as a plant-based meat substitute has raised concerns about excessive isoflavone intake. Therefore, the production of isoflavone-free soybean has been anticipated.
View Article and Find Full Text PDFStudy on Time Distribution and Pathogenic Bacteria of Infection After Auricular Reconstruction With Tissue Expansion for Microtia.
J Craniofac Surg
January 2025
Plastic Surgery Hospital and Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Postoperative infection is one of the main complications that affect the surgical effect of auricular reconstruction with tissue expansion. Understanding the susceptible time and distribution of pathogens is especially important for the treatment.
Method: The data of patients with infection after auricular reconstruction with tissue expansion from September 1, 2018 to August 30, 2024 were collected retrospectively.
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