Colitis as a Harmful Mimicker of Inflammatory Bowel Disease.

Case Rep Pathol

Department of Pathology, University of Miami Health System/Jackson Memorial Hospital, 1611 NW 12th Ave, Holtz Center 2142D, Miami, FL 33136, USA.

Published: May 2017

AI Article Synopsis

  • * Her symptoms included abdominal pain, diarrhea, and blood in stool, and while colonoscopy suggested inflammatory bowel disease, biopsies revealed parasites, pointing to autoinfection.
  • * The incident highlights the need for careful diagnosis when faced with similar symptoms since misidentification can result in severe consequences and different treatment paths.

Article Abstract

Autoinfection caused by frequently becomes a life-long disease unless it is effectively treated. There is overlapping histomorphology between colitis and inflammatory bowel disease; a low index of suspicion can lead to misdiagnosis and fatal consequences. We present a case of colitis mimicking the clinical and pathologic features of inflammatory bowel disease. A 64-year-old female presented to the emergency department with a four-day history of abdominal pain, diarrhea, and hematochezia. Colonoscopy revealed diffuse inflammation suggestive of inflammatory bowel disease, which led to initiation of 5-aminosalicylic acid and intravenous methylprednisolone. Biopsies of the colon revealed increased lymphoplasmacytic infiltrate of the lamina propria with eosinophilic microabscesses and presence of larvae, consistent with . Immunosuppressive medication was halted. The patient ultimately died a few days later. This case emphasizes the importance of identifying the overlapping clinical and pathologic features of colitis and inflammatory bowel disease. A high index of suspicion and recognition of particular histological findings, including eosinophilic microabscesses, aid in the correct diagnosis. Definitive diagnosis is crucial as each disease carries distinct therapeutic implications and outcome.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438857PMC
http://dx.doi.org/10.1155/2017/2560719DOI Listing

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