Karma is the ancient Indian philosophy of cause and effect, which implies that an individual's intentions, and actions, both have consequences. None can escape the consequences of one's actions. Applying the principle of karma to medicine and healthcare, the significance of optimal and timely interventions at various stages of disease, may be realized. A holistic approach to metabolic control in diabetes translates into improved clinical outcomes, as evident from the result of STENO-2, EMPA-REG OUTCOME, or LEADER trials. The principle of karma in the management of diabetes may have implications at the transgenerational level during pregnancy and nursing, at the individual patient-level based on phenotype, and at the community level in preventive medicine. The concept of metabolic karma can be used as an effective motivational tool to encourage better health care seeking behavior and adherence to prescribed interventions.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434738 | PMC |
| http://dx.doi.org/10.4103/ijem.IJEM_571_16 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Management of Chronic Plaque Psoriasis through Panchkarma: A case report.
J Ayurveda Integr Med
January 2025
Dept. of Panchakarma, National Institute of Ayurveda, Jaipur, India.
Psoriasis is a chronic systemic inflammatory skin disorder prevailing in 2%-3% individuals worldwide. Yet no permanent management has been established. Metabolic burdens and comorbidities have been found to be associated with Psoriasis, which make it more critical.
View Article and Find Full Text PDFDisruptive effects of genistein and daidzein on steroidogenesis, testicular development and maturation of Cyprinus carpio (Linn, 1758) males.
Fish Physiol Biochem
January 2025
Fish Nutrition, Biochemistry and Physiology Division, ICAR-Central Institute of Fisheries Education, Versova, Andheri West, Mumbai, 400061, Maharashtra, India.
A 60-day feeding trial was conducted to evaluate the combined effect of dietary soy phytoestrogens, specifically genistein and daidzein, on the gonadal recrudescence and maturation of male Cyprinus carpio (Linnaeus, 1758). Adult male C. carpio (60 ± 10 g) were fed with a diet with no added genistein or daidzein (C), 110 mg/100 mg genistein (GL), 210 mg/100 g genistein (GH), 4 mg/100 g daidzein (DL), 8 mg/100 g daidzein (DH), combination of 110 mg/100 mg genistein and 4 mg/100 g daidzein (DGL, equivalent to 17.
View Article and Find Full Text PDFGenerating a Peptide Library Using the Repeats of Amino Acid Scaffolds Created by Sliding the Framework of a 7-mer Human Chemerin Segment and Discovery of Potent Antibacterial and Antimycobacterial Peptides.
J Med Chem
January 2025
Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031, India.
The quest for new approaches for generating novel bioactive designer proteins/peptides has continued with their success in various biomedical applications. Previously, we designed a 14-mer α-helical peptide with antimicrobial and antimycobacterial activities by employing a tandem repeat of the 7-mer, "KVLGRLV" human chemerin segment. Herein, we devised a new method of "sliding framework" with this segment to create amino acid scaffolds of varying sizes and sequences and explored the design of a peptide library with antibacterial and antimycobacterial activities.
View Article and Find Full Text PDFRole of ryanodine receptor cooperativity in Ca-wave-mediated triggered activity in cardiomyocytes.
J Physiol
December 2024
Physics Department and Center for Interdisciplinary Research in Complex Systems, Northeastern University, Boston, MA, USA.
Ca waves are known to trigger delayed after-depolarizations that can cause malignant cardiac arrhythmias. However, modelling Ca waves using physiologically realistic models has remained a major challenge. Existing models with low Ca sensitivity of ryanodine receptors (RyRs) necessitate large release currents, leading to an unrealistically large Ca transient amplitude incompatible with the experimental observations.
View Article and Find Full Text PDFArticle Synopsis
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!