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Diagnosing a genetic disease in a donor-conceived child: case report and discussion of the ethical, legal, and practical issues.
Pediatr Nephrol
October 2024
Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, M5G 1X8, Canada.
We describe the unexpected challenges pediatricians may experience when children conceived with assisted reproduction are diagnosed with a rare genetic condition. A local case series triggered a dialogue between many stakeholders with varied expertise. Indeed, diagnosing a genetic disease in a child conceived by embryo, egg, or sperm donation is becoming more common now that genetic testing and in vitro fertilization (IVF) are readily accessible.
View Article and Find Full Text PDFIntroduction: Parents who use donated gametes or embryos to form their families struggle with telling their children about their genetic origins. We developed the Tool to Empower Parental Telling and Talking (TELL Tool) to support parents in disclosure to their children and an eBook attention control.
Method: A randomized parallel, two-group, attention-controlled clinical pilot trial was conducted online during COVID-19.
Perspectives on sperm donor anonymity: insights from donor-conceived adults in Belgium.
Hum Reprod
September 2024
Brussels IVF Centre for Reproductive Medicine, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
Study Question: Are donor-conceived adults in Belgium interested in obtaining donor information, and do these interests vary based on their family backgrounds?
Summary Answer: Donor-conceived adults express a significant interest in obtaining donor-related information, with the highest interest reported by offspring from heterosexual couples compared to those from lesbian couple-parented or single-parent families.
What Is Known Already: In Belgium, sperm donation is mainly anonymous, but the rise of direct-to-consumer genetic testing challenges this anonymity.
Study Design, Size, Duration: This was a cross-sectional study involving an online nationwide survey conducted from July 2022 to October 2023.
Comparing the psychological outcomes of donor and non-donor conceived people: A systematic review.
BJOG
December 2024
Department of Women and Children's Health, King's College London, London, UK.
Background: Over 70 000 donor-conceived (DC) people have been born in the UK since 1991. Little is known about their long-term psychological outcomes and no systematic review has assessed these.
Objectives: To conduct a systematic review of the psychological experiences of DC people through childhood and adulthood (Prospero: CRD42021257863).
One size does not fit all: the personal nature of completed embryo donation.
J Assist Reprod Genet
July 2024
Department of Obstetrics and Gynecology, Northwestern University, Chicago, IL, USA.
Article Synopsis
- The study looked at why people in the U.S. choose to donate embryos they don’t use after IVF treatment.
- A survey was sent to people interested in donating embryos, and 337 people shared their decisions: 230 donated, 75 tossed them, and 25 were unsure.
- The choice to donate was influenced by personal beliefs, concerns for future kids, and feelings about embryos, with those who donated feeling happier with their decision than those who discarded them.
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