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Chili pepper consumption and duration of fissure symptoms onset are associated with perianal fistula development among patients with anal fissure: a case-control study.
BMC Nutr
December 2024
Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Perianal fistula is one of the complications of deepened anal fissure. The present case-control study aimed to assess the risk factors of fissure-associated fistulas due to the limited available evidence.
Methods: Patients with fissure-associated fistulas were considered as case, and patients with anal fissure who were undergoing medical treatment without any previous anorectal surgeries were considered as control group.
Self -reported bruxism in patients undergoing Orthodontic treatment - a cross-sectional study.
BMC Oral Health
December 2024
Department of Surgery, Program Director Orthodontics Residency Program, Section of Dentistry, The Aga Khan University Hospital, Stadium Road, P.O Box 3500, Karachi, 74800, Pakistan.
Background: Orthodontic treatment involves manipulation of tooth position that can temporarily lead to occlusal interferences capable of inducing bruxism. The objectives of this study were to determine the self-reported incidence of bruxism and its association with factors such as facial type, divergence, skeletal and dental malocclusions in orthodontic patients.
Materials And Methods: 80 patients who underwent a minimum of six months of orthodontic treatment were surveyed using a validated self-reported bruxism questionnaire for the presence or absence of bruxism.
Disproportionality Analysis of Hepatotoxic and Gastrointestinal Adverse Events Associated With Nintedanib Using the Japanese Adverse Drug Event Report (JADER) Database.
In Vivo
December 2024
School of Pharmacy, Hyogo Medical University, Kobe, Japan;
Background/aim: Nintedanib may cause adverse events such as elevated liver enzyme levels, diarrhea, and decreased appetite. These adverse events should be managed appropriately as they affect the quality of life of patients. This study has aimed to analyze patient characteristics and time-to-onset of adverse events caused by nintedanib using the Japanese Adverse Drug Event Report (JADER) database.
View Article and Find Full Text PDFTuberculosis screening among cough suppressant buyers in pharmacies and drug outlets in Guinea: a cross-sectional study.
BMJ Open Respir Res
December 2024
World Health Organization, Geneva, Switzerland.
Background: Tuberculosis (TB) poses a significant public health challenge in Guinea, with an estimated 22 000 TB cases in 2020; an estimated 6125 (28%) cases went undetected. We evaluated an intensified TB case finding strategy in Guinea which targeted customers who bought cough suppressants from pharmacies or drug outlets.
Methods: We involved 25 pharmacies and 25 drug outlets in Matoto, Conakry, Guinea.
Global, regional, and national burden of very early-onset colorectal cancer and its risk factors from 1990 to 2019: A systematic analysis for the global burden of disease study 2019.
Neoplasia
December 2024
Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, 430060, Hubei Province, China. Electronic address:
Aims: Very early-onset colorectal cancer (EOCRC) was defined as CRC diagnosed before the age of 35 proposed by the latest EOCRC management guideline. Until now, the disease burden of very EOCRC has never been reported. This study aimed to explore the burden of very EOCRC across the past three decades.
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