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Complete genome sequence of the marine mangrove fungus Sarcopodium sp.QM3-1 confirmed its high potential for antimicrobial activity.
Mar Genomics
March 2025
Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 178 Daxue Road, Xiamen 361005, China; Applied Technology Engineering Center of Fujian Provincial Higher Education for Marine Resource Protection and Ecological Governance, Xiamen Key Laboratory of Intelligent Fishery, School of Marine Biology, Xiamen Ocean Vocational College, Xiamen 361100, China; Co-Innovation Center of Jiangsu Marine Bioindustry Technology, Jiangsu Ocean University, Lianyungang 222005, China. Electronic address:
Mangroves, owing to their unique living environment, serve as an important source of natural bioactive compounds. Sarcopodium sp. QM3-1, a marine fungus isolated from mangrove sediments of Quanzhou Bay, exhibited antifungal activity against the plant pathogen Agrobacterium tumefaciens and Magnaporthe oryzae.
View Article and Find Full Text PDFThe complete genome sequence of Stenotrophomonas sp. P2112 for genome mining of polyvinyl chloride degrading enzymes.
Mar Genomics
March 2025
College of Environment and Ecology, Xiamen University, Xiamen 361005, Fujian, China. Electronic address:
Stenotrophomonas sp. P2112, isolated from a marine sediment sample of the Pacific Ocean, can grow in mineral medium with polyvinyl chloride (PVC) plastic as sole carbon source. Here, we present the complete genome of Stenotrophomonas sp.
View Article and Find Full Text PDFGenetically-modified activation strategy facilitates the discovery of sesquiterpene-derived metabolites from .
Synth Syst Biotechnol
June 2025
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.
Genome mining has revealed that spp. possess numerous down-regulated or cryptic biosynthetic gene clusters (BGCs). This finding hinted that our investigation of fungal secondary metabolomes is limited.
View Article and Find Full Text PDFSalvicsite A-C: Three Seco-Norabietane Diterpenoids Including an Unusual Tetracyclic Skeleton from Diels f. Stib.
J Org Chem
January 2025
School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.
Three seco-norabietane diterpenoids, salvicsites A-C (-), along with two known compounds, were isolated from the roots and rhizomes of Diels f. Stib. Salvicsite A () represents an unprecedented structural combination, featuring an eight-membered α-methyl-α,β-unsaturated lactone ring and a five-membered α,β-unsaturated lactone ring, based on a 6/6/5/8 ring system.
View Article and Find Full Text PDFCrepidamycins A-E, pyranonaphthoquinones from endophytic Streptomyces sp. MG-F-1 of Dendrobium crepidatum by the co-culture strategy.
Phytochemistry
January 2025
Jiangsu Key Laboratory for Functional Substances of Chinese Medicine, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China; State Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address:
On the basis of the co-culture strategy, five previously undescribed S-bridged pyranonaphthoquinones, crepidamycins A-E (1-5) and five known analogues (6-10) were isolated from a medicinal plant endophytic Streptomyces sp. MG-F-1 in Dendrobium crepidatum with Bacillus cereus MG-1. The structures and absolute configurations of 1-5 were elucidated by the interpretation of data from detailed spectroscopic analysis and electronic circular dichroism spectra, together with consideration of the biogenetic origins.
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