This paper describes neonatal intensive care units (NICU) in Italy using a set of organizational variables identifying management profile. The correlations between variables, and how these are impacted by structural aspects of the department or hospital, are investigated. The research was conducted within the 5-year far-reaching and complex SONAR study run by the Italian Neonatal Network, which maps NICU, monitors outcomes of member centres, defines organizational models, and identifies best practices to improve care quality. Seven variables relating to activities, organization processes, and behaviour models used in the SONAR study were used here to assess NICU. Data from 54 Italian NICUs, 1601 nursing staff, and 643 doctors were used. We identified high levels of variation in NICUs for all aspects of organization. We also identified important opportunities for improvement, especially in the areas of performance measurement, quality improvement, and learning for healthcare staff. In terms of structural characteristics, we identified big differences between NICUs in the north and south of Italy. The findings provide a description of NICUs in Italy and identify a set of variables useful for management in assessing NICU, which are among the most complex and costly operational units in a hospital.
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Cytokine
January 2025
College of technical engineering, the Islamic University, Najaf, Iraq; College of technical engineering, The Islamic University of Al Diwaniyah, Diwaniya, Iraq; College of technical engineering, The Islamic University of Babylon, Hillah, Iraq.
Inflammation, driven by various stimuli such as pathogens, cellular damage, or vascular injury, plays a central role in numerous acute and chronic conditions. Current treatments are being re-evaluated, prompting interest in naturally occurring compounds like kaempferol, a flavonoid prevalent in fruits and vegetables, for their anti-inflammatory properties. This study explores the therapeutic potential of kaempferol, focusing on its ability to modulate pro-inflammatory cytokines and its broader effects on inflammatory signaling pathways.
View Article and Find Full Text PDFCureus
November 2024
Diagnostic Radiology, University of Arkansas for Medical Sciences, Little Rock, USA.
Background: Accurate diagnosis and understanding of brain disorders are crucial for the best treatment. While multimodal neuroimaging is essential, it has its limitations. Conventional computed tomography (CT) and magnetic resonance imaging (MRI) provide detailed anatomical information but lack molecular insights, while 18F-fluorodeoxyglucose-positron emission tomography (FDG PET) offers metabolic data but often has limited spatial resolution.
View Article and Find Full Text PDFJ Acoust Soc Am
December 2024
Nicholas School of the Environment, Duke University, Durham, North Carolina 27708, USA.
Marine mammals are known to respond to various human noises, including and in certain cases, strongly, to military active sonar. Responses include small and short-term changes in diving behavior, horizontal avoidance of an ensonified area, and mass strandings. Considerable research has been conducted using short-term biologging tags to understand these responses.
View Article and Find Full Text PDFRes Pharm Sci
October 2024
BioGenomics Ltd, Maharastra, India.
Background And Purpose: To compare the efficacy, safety, and immunogenicity of recombinant insulin aspart 100 U/mL manufactured by BioGenomics Limited (BGL-ASP) with innovator NovoRapid in type 2 diabetes mellitus patients (T2 DM).
Experimental Approach: This was a multicenter, open-label, randomized, parallel-group study in T2 DM patients, on premix human insulin therapy ± oral anti-diabetics. Besides self-monitored plasma glucose, fasting and post-prandial plasma glucose (FPG and PPG) were tested at baseline, week 12, and week 24.
Sensors (Basel)
November 2024
College of Fisheries, Guangdong Ocean University, Zhanjiang 524088, China.
Underwater simultaneous localization and mapping (SLAM) has significant challenges due to the complexities of underwater environments, marked by limited visibility, variable conditions, and restricted global positioning system (GPS) availability. This study provides a comprehensive analysis of sensor fusion techniques in underwater SLAM, highlighting the amalgamation of proprioceptive and exteroceptive sensors to improve UUV navigational accuracy and system resilience. Essential sensor applications, including inertial measurement units (IMUs), Doppler velocity logs (DVLs), cameras, sonar, and LiDAR (light detection and ranging), are examined for their contributions to navigation and perception.
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