AI Article Synopsis
- A 27-year-old male chimpanzee was diagnosed with thrombotic thrombocytopenic purpura (TTP), a serious blood disorder.
- The underlying issue was found to be a deficiency in the enzyme ADAMTS13.
- After receiving high-dose prednisone treatment, both the chimpanzee’s blood values and clinical symptoms improved, marking a unique case in non-human primates.
Article Abstract
A 27-year-old male chimpanzee (Pan troglodytes verus) developed signs of thrombotic thrombocytopenic purpura (TTP). ADAMTS13 deficiency appeared to be the cause of disease. After treatment with high-dose prednisone, haematological values and clinical signs recovered. This is the first description of spontaneous TTP associated with ADAMTS13 deficiency in a non-human primate.
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| http://dx.doi.org/10.1111/jmp.12278 | DOI Listing |
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