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[Case No. 6: Placental cytomegalovirus infection].
Ann Pathol
January 2025
UF de fœtopathologie, hôpital Robert-Debré, 49, boulevard Sérurier, 75019 Paris, France. Electronic address:
Predictors of cytomegalovirus infection in patients with connective tissue disease treated by pulsed methylprednisolone therapy: a multicenter retrospective cohort study.
BMC Infect Dis
January 2025
Department of Dermatology, Showa University School of Medicine, 1-5-8, Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan.
Article Synopsis
- This study investigates predictors of cytomegalovirus (CMV) infection in immunosuppressed patients with connective tissue disease undergoing pulsed-methylprednisolone (p-MPSL) therapy.
- It is a retrospective cohort study that analyzed 200 patients' data, identifying key baseline characteristics linked to increased risk of CMV infection, including age, platelet count, lymphocyte count, and specific blood ratio metrics.
- The findings highlight that older age and low blood cell counts significantly elevate the likelihood of CMV antigen positivity, providing insights for risk assessment in similar patient populations.
Upadacitinib: the JAK inhibitor that achieved what other drugs could not.
Rev Esp Enferm Dig
January 2025
Gastroenterology, Hospital Universitario Infanta Elena, Spain.
We present an interesting case of severe ulcerative colitis flare, of challenging management because of a cytomegalovirus co-infection, in which upadacitinib achieved clinical and biochemical remission after poor responses to ganciclovir and tofacitinib.
View Article and Find Full Text PDFLiving donor uterus transplant research project in Singapore: Progress of the first case.
Acta Obstet Gynecol Scand
January 2025
Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Introduction: To report the progress of the human living uterus transplant research project in Singapore.
Material And Methods: The uterus transplant research project began in 2012 with a collaboration between the Swedish and Singapore teams. Ethics approval was obtained from the SingHealth Centralised Institutional Review Board, the SingHealth Transplant and the Singapore General Hospital Biomedical Ethics Committee to perform 5 uterus transplant procedures in a collaborative multi-site research study at the Singapore General Hospital.
Sapovirus-Associated Diarrhea in Renal Transplant Patient Treated Without Altering Immunosuppression.
Indian J Nephrol
June 2024
Department of Critical Care Medicine, Apollo Health City, Hyderabad, India.
Solid organ transplant (SOT) recipients are at increased risk of infective diarrheas. In such patients, diarrhea can be complicated by dehydration, leading to acute kidney injury or vascular thrombosis. Viral diarrhea in SOT is reported to be commonly due to cytomegalovirus and norovirus.
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