Intracanal medicaments play a vital role in disinfection of root canal system. The aim of this study was to evaluate intratubular penetration and fracture resistance of roots filled with micron- and nano-sized intracanal medicaments: calcium hydroxide (CH), nanocalcium hydroxide (NCH), chitosan (CS) and nanochitosan (NCS). Their antibacterial effect on E. faecalis was tested using agar diffusion method. NCH and NCS were prepared by precipitation method and ionic crosslinking respectively. NCH and NCS particles were spherical, with an average particle size of 102±11.3nm and 130±17.6nm respectively. The medicaments were filled in extracted human teeth. Depth of penetration of the medicaments into dentinal tubules at coronal (C), middle (M) and apical (A) thirds was measured. Fracture resistance of the teeth was evaluated after 1 week and 1-month intervals. NCH showed the highest depth of penetration (C ∼746.98μm, M ∼700.30μm, A ∼134.69μm). CS showed the highest fracture resistance, whereas no significant difference was found between other medicaments, at both the time intervals. NCH (8.07±0.06) and NCS (8.13±0.06) showed significantly higher zone of inhibition than CH (7.7±0.17) and CS (7.37±0.15). Under the conditions of this study, it can be concluded that NCH and NCS can be used as potential intracanal medicaments.
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http://dx.doi.org/10.1016/j.ijbiomac.2017.05.126 | DOI Listing |
J Endod
January 2025
School of Medicine and Dentistry, Griffith University, Gold Coast, Queensland, Australia. Electronic address:
Introduction: This in vitro study assessed how shade changes induced by endodontic medicaments affect the transmission of single and multiples wavelengths of infrared light through enamel and dentin.
Methods: Eighteen extracted single-rooted permanent teeth were prepared, removing all extrinsic staining, and cementum. Tooth slices were treated for 4 weeks with UltraCal™ XS, Ledermix™, or were untreated controls.
Objective This in vitro study aimed to assess and compare the antimicrobial effectiveness of ampicillin with ceftriaxone (AC), diclofenac sodium (DS), modified triple antibiotic paste (MTAP), and calcium hydroxide (CH) against in root canal systems. Materials and methods The antimicrobial activity of the medicaments was assessed by determining the minimum inhibitory concentrations (MIC) via the agar well diffusion method. A total of 40 extracted permanent teeth underwent root canal treatment, and was introduced into the canal preparations.
View Article and Find Full Text PDFAm J Case Rep
January 2025
Department of Restorative Dentistry, College of Dentistry, Umm Al-Qura University, Mekkah, Saudi Arabia.
BACKGROUND Internal root resorption (IRR) is a rare dental condition characterized by the progressive resorption of dentin within the root canal, often resulting from infection, trauma, or orthodontic treatment. When IRR progresses to perforation, it creates a communication pathway with periodontal tissues, necessitating effective endodontic therapy and perforation repair. Bioceramic sealers, known for their biocompatibility and flowability, have emerged as a promising alternative to traditional materials for filling and sealing the root canal system.
View Article and Find Full Text PDFJ Oral Sci
January 2025
Department of Conservative Dentistry, School of Dentistry and Institute of Oral Bioscience, Jeonbuk National University.
Purpose: This study investigated the synergistic effects of reduced graphene oxide (RGO) on the antibacterial activity of three calcium hydroxide-based intracanal medicaments with different vehicles.
Methods: Multispecies biofilms were cultured in a bovine root canal model. Intracanal medicaments containing nonaqueous vehicles, including N-methyl-2-pyrrolidone (NMP; CleaniCal), propylene glycol (PG; UltraCal XS), and polyethylene glycol (PEG; Calcipex II), were placed in the model.
J Conserv Dent Endod
November 2024
Department of Conservative Dentistry and Endodontics, Chhattisgarh Dental College and Research Institute, Rajnandgaon, Chhattisgarh, India.
Background: Intracanal medicament (ICM) eliminates remaining bacteria and their toxins that were not removed by chemomechanical preparation during endodontic treatment.
Aim: The aim of this study was to compare and evaluate the removal of ozonated oil-based, silicone oil-based, and distilled water-based ICM with two calcium chelators, i.e.
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