AI Article Synopsis
- Researchers are tackling the challenge of controlling the shape and function of polymeric nanostructures during self-assembly for applications in materials and biomedical science.
- The study introduces a method using amphiphilic block copolypept(o)ides that enables separate adjustment of core properties and function, allowing for bioreversible transformations.
- By utilizing secondary-structure formation inherent to peptides, they can create different structures, like spherical and worm-like architectures, from the same block copolymer, making it a versatile approach for developing peptide-based nanostructures.
Article Abstract
Achieving precise control over the morphology and function of polymeric nanostructures during self-assembly remains a challenge in materials as well as biomedical science, especially when independent control over particle properties is desired. Herein, we report on nanostructures derived from amphiphilic block copolypept(o)ides by secondary-structure-directed self-assembly, presenting a strategy to adjust core polarity and function separately from particle preparation in a bioreversible manner. The peptide-inherent process of secondary-structure formation allows for the synthesis of spherical and worm-like core-cross-linked architectures from the same block copolymer, introducing a simple yet powerful approach to versatile peptide-based core-shell nanostructures.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/anie.201702624 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!