Two new flavonoids from Artemisia argyi with their anticoagulation activities.

Nat Prod Res

a School of Pharmacy , Xinxiang Medical University, Xinxiang , People's Republic of China.

Published: March 2018

A new flavone glycoside, eupatilin 7-O-β-d-glucopyranoside (1) and a new flavone, 5,6,2',4'-tetrahydroxy-7,5'-dimethoxyflavone (2), were isolated from Artemisia argyi. Their structures were unambiguously elucidated by extensive spectroscopic analysis. Both flavonoids were evaluated for in vitro anticoagulation activities. Compound 1 significantly extended thrombin time. Compound 2 had obvious effect in increasing prothrombin time.

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http://dx.doi.org/10.1080/14786419.2017.1332603DOI Listing

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