A review of all fine needle aspiration biopsies of salivary gland lesions performed at the Flinders Medical Centre during a 9-year period revealed a number of cases in which there was a discrepancy between the initial cytology report and the definitive diagnosis by histology examination. The most common problem was that of atypical features in pleomorphic adenoma, raising a suspicion of a low-grade malignant tumour in 4 cases. One mucoepidermoid carcinoma and one acinic cell carcinoma had been wrongly diagnosed as Warthin's tumours on the basis of the presence of sheets of bland epithelial cells with oncocyte-like cytoplasm. One trabecular monomorphic adenoma was misdiagnosed as adenoid cystic carcinoma, and one adenoid cystic carcinoma as pleomorphic adenoma. The cytologic patterns of these cases are presented and discussed.
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http://dx.doi.org/10.3109/00313028809085213 | DOI Listing |
Background: Angioimmunoblastic T-cell lymphoma (AITL) is a distinct subtype of peripheral T-cell lymphoma (PTCL) and accounts for 2% of all non-Hodgkin lymphomas. Its typical characteristics include an aggressive course, progressive lymphadenopathy, hepatosplenomegaly, systemic symptoms, anemia, hypergammaglobulinemia, and generally poor prognosis.
Methods: We describe a rare case in which the left inguinal lymph node was completely excised and biopsied one year ago.
Endocr Connect
January 2025
H Qu, Department of Endocrinology, The Second Affiliated Hospital of Army Medical University, Chongqing, China.
Subacute thyroiditis (SAT) is an inflammatory thyroid disease characterized by neck pain, tenderness, general symptoms, and thyroid dysfunction. Despite gaining new insights into the epidemiology, pathogenesis, and treatment of SAT in recent years, the exact pathogenesis and determinants of its clinical progression remain unclear. Here, we profiled thyroid in situ protein alterations in fine needle aspiration biopsy samples from SAT patients using proteomic analysis and uncovered 57 differentially abundant proteins.
View Article and Find Full Text PDFHealth Sci Rep
January 2025
Gerhard-Domagk Institute of Pathology University Hospital Muenster (UKM) Muenster Germany.
Background And Aims: Benign lesions, inflammation, cysts and pseudocysts, as well as neoplasms of the exocrine and endocrine parts of the pancreas can be easily identified using cytological methods. The sensitivity and specificity can be increased with the help of additional examination methods. The sensitivity of intraoperative rapid cytology reaches about 99%.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Department of Otorhinolaryngology Head and Neck Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Tracheal adenoid cystic carcinoma is a rare malignancy. We report the case of a 65-year-old male who presented to our department due to a 3-month history of mild dysphagia without other associated symptoms. The neck, laryngeal, and hypopharyngeal examinations were normal.
View Article and Find Full Text PDFJ Pediatr Orthop
January 2025
Department of Orthopaedic Surgery, Nationwide Children's Hospital.
Background: Biopsy is an essential part of proper diagnostic workup in pediatric bone sarcomas impacting surgical planning, chemotherapeutic treatments, and prognostic determination. Two main biopsy techniques are currently used: closed biopsy (core needle or fine needle aspiration) and open biopsy. Historical oncologic teaching is for resection of the biopsy tract with the tumor specimen due to the theoretical risk for biopsy tract tumor contamination; however, this can restrict surgical planning and increase morbidity.
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