Post-translational regulation of plant immunity.

Curr Opin Plant Biol

Howard Hughes Medical Institute, Department of Biology, Duke University, Durham, NC 27708, USA.

Published: August 2017

AI Article Synopsis

  • Plants have developed sophisticated molecular defenses to fend off pathogens, primarily through post-translational modifications (PTMs) that quickly adjust their immune signaling pathways.
  • PTMs play a crucial role in regulating plant immune responses and are also exploited by pathogens to undermine host defenses via effector proteins they secrete into the host cells.
  • Recent research has enhanced our understanding of how PTMs contribute to effective plant immunity, portraying a more comprehensive picture of the immune strategies employed by plants.

Article Abstract

Plants have evolved multi-layered molecular defense strategies to protect against pathogens. Plant immune signaling largely relies on post-translational modifications (PTMs) to induce rapid alterations of signaling pathways to achieve a response that is appropriate to the type of pathogen and infection pressure. In host cells, dynamic PTMs have emerged as powerful regulatory mechanisms that cells use to adjust their immune response. PTM is also a virulence strategy used by pathogens to subvert host immunity through the activities of effector proteins secreted into the host cell. Recent studies focusing on deciphering post-translational mechanisms underlying plant immunity have offered an in-depth view of how PTMs facilitate efficient immune responses and have provided a more dynamic and holistic view of plant immunity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644497PMC
http://dx.doi.org/10.1016/j.pbi.2017.05.004DOI Listing

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