At present, the European Higher Education Area (EHEA) emphasizes the importance of collaborative learning in University education. Previous studies have found evidence to support collaborative activities; however, none have analyzed the influence of contact networks among students on their engagement and performance. This paper reports an intervention with nursing degree students aimed at facilitating an interdependent network to promote engagement and improve academic performance. The intervention was based on recording a video during a case study. The variables analyzed were network centrality, engagement and performance. The UCINET program was used to analyse social networks. The results showed a more cohesive network after the intervention and a high level of academic performance. The use of contact networks among students could be used as an academic strategy to build bridges between students in the classroom and even between these and students in other classrooms or centres.
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http://dx.doi.org/10.1007/s10916-017-0747-y | DOI Listing |
Semin Oncol Nurs
January 2025
Bavarian Cancer Research Center and CCC Munich LMU, LMU Hospital Munich, Germany.
Objectives: Robust evidence highlights the crucial role of nutrition for people with cancer, and international organizations recognize it as a basic human right linked to health and food. Within this context, we aim to emphasize the critical role of nutrition care for cancer patients and to highlight the essential contributions of nurses in providing patient-centered nutrition care.
Methods: This opinion paper synthesizes evidence and perspectives from peer-reviewed articles and position papers.
Am J Hum Genet
January 2025
Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany; Institute of Human Genetics, University of Regensburg, 93053 Regensburg, Germany; Institute of Clinical Human Genetics, University Hospital Regensburg, 93053 Regensburg, Germany. Electronic address:
BCL11B is a Cys2-His2 zinc-finger (C2H2-ZnF) domain-containing, DNA-binding, transcription factor with established roles in the development of various organs and tissues, primarily the immune and nervous systems. BCL11B germline variants have been associated with a variety of developmental syndromes. However, genotype-phenotype correlations along with pathophysiologic mechanisms of selected variants mostly remain elusive.
View Article and Find Full Text PDFBioinformatics
January 2025
School of Engineering, Westlake University, Hangzhou, 310024, China.
Motivation: Drug-target interaction (DTI) prediction is crucial for drug discovery, significantly reducing costs and time in experimental searches across vast drug compound spaces. While deep learning has advanced DTI prediction accuracy, challenges remain: (i) existing methods often lack generalizability, with performance dropping significantly on unseen proteins and cross-domain settings; (ii) current molecular relational learning often overlooks subpocket-level interactions, which are vital for a detailed understanding of binding sites.
Results: We introduce SP-DTI, a subpocket-informed transformer model designed to address these challenges through: (i) detailed subpocket analysis using the Cavity Identification and Analysis Routine (CAVIAR) for interaction modeling at both global and local levels, and (ii) integration of pre-trained language models into graph neural networks to encode drugs and proteins, enhancing generalizability to unlabeled data.
Cell Rep
January 2025
Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Erling Skjalgssons Gate 1, 7491 Trondheim, Norway; Kavli Institute for Systems Neuroscience and Centre for Algorithms in the Cortex, Norwegian University of Science and Technology, Olav Kyrres Gate 9, 7030 Trondheim, Norway. Electronic address:
The brain uses a specialized system to transport cerebrospinal fluid (CSF), consisting of interconnected ventricles lined by motile ciliated ependymal cells. These cells act jointly with CSF secretion and cardiac pressure gradients to regulate CSF dynamics. To date, the link between cilia-mediated CSF flow and brain function is poorly understood.
View Article and Find Full Text PDFSensors (Basel)
December 2024
School of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Due to its non-contact characteristics, remote photoplethysmography (rPPG) has attracted widespread attention in recent years, and has been widely applied for remote physiological measurements. However, most of the existing rPPG models are unable to estimate multiple physiological signals simultaneously, and the performance of the limited available multi-task models is also restricted due to their single-model architectures. To address the above problems, this study proposes MultiPhys, adopting a heterogeneous network fusion approach for its development.
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