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Modified Approach to Segmental Maxillary Surgery: Midline Osteotomy and Parasagittal Soft Tissue Incisions.
J Oral Maxillofac Surg
December 2024
Clinical Professor Department of Oral and Maxillofacial Surgery and Orthodontics, Texas A&M University College of Dentistry, Dallas, TX; Private Practice Baylor University Medical Center, Dallas, TX.
Traditional surgical techniques for segmental maxillary surgery include a combination of interdental osteotomies with paramidline bony cuts while keeping the palatal soft tissue intact. Besides surgical complexity, segmental maxillary procedures have been associated with higher incidence of relapse and complications. We present our experience with specific hard- and soft-tissue modifications (midline bony osteotomy and reflection of palatal soft tissue with carefully designed incisions) which will allow surgeons to perform larger expansions with a low incidence of complications and decreased relapse.
View Article and Find Full Text PDFPaper-Based Device for Phenolic Content Determination in Tea Extracts.
Phytochem Anal
December 2024
Department of Chemistry, Colorado State University, Fort Collins, Colorado, USA.
Introduction: Phenolic compounds garner interest in developing medicines, nutraceuticals, and cosmeceuticals based on natural products. The quantity of phenolic compounds in a sample is commonly determined via spectrophotometry; however, this instrumented technique is relatively laborious and time consuming and requires a large amount of reagents.
Objective: This work aimed to develop a simple, point-of-need colorimetric sensor to rapidly determine total phenolic content (TPC) in tea extracts.
Magnetophoretic slider assay for electrochemical detection of SARS-cov-2 nucleocapsid protein in nasal swab samples.
Biosens Bioelectron
March 2025
Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA; School of Biomedical Engineering, Colorado State University, CO, USA, 80523; Department of Chemical and Biological Engineering, Colorado State University, CO, USA, 80523. Electronic address:
The COVID-19 pandemic highlighted the need for rapid and sensitive diagnostic tools. In this work, the Magnetophoretic Slider Assay (MeSA) was integrated with electrochemical detection (eMeSA) using screen-printed carbon electrodes for the first time for the detection of SARS-CoV-2 nucleocapsid protein (NP). A sandwich enzyme-linked immunosorbent assay (ELISA) was performed on streptavidin-labeled magnetic beads (MBs).
View Article and Find Full Text PDFMost insects were dead when they were named by taxonomists, and predominantly morphological criteria have been used for more than two centuries. But in nature there are populations with individuals looking identical, that turn out to represent two or more different species, and others that look different but are single biological species. Coastal and several continental populations of the green lacewing Chrysoperla mediterranea (Hölzel 1972) had been considered to be one species, based on identical precopulatory "song patterns" (Henry et al.
View Article and Find Full Text PDFThe Role of Phase Separation and Local Mobility in the Stabilization of a Lyophilized IgG2 Formulation.
AAPS PharmSciTech
November 2024
Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, 40526, USA.
The utility of employing solid-state NMR (SSNMR) to assess parameters governing the stability of a lyophilized IgG2 protein was the focus of the present work. Specifically, the interaction between the sugar stabilizer (sucrose) and protein component was measured using SSNMR and compared to physical and chemical stability data obtained from thermally stressed samples. H T and H T relaxation times were measured by SSMNR for 5 different formulation conditions, and the resultant values were used to examine local mobility and phase separation, respectively.
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