The author relates his intellectual journey from eye-testing clinician to experimental vision scientist. Starting with the quest for underpinning in physics and physiology of vague clinical propositions and of psychology's acceptance of thresholds as "fuzzy-edged," and a long career pursuing a reductionist agenda in empirical vision science, his journey led to the realization that the full understanding of human vision cannot proceed without factoring in an observer's awareness, with its attendant uncertainty and open-endedness. He finds support in the loss of completeness, finality, and certainty revealed in fundamental twentieth-century formulations of mathematics and physics. Just as biology prospered with the introduction of the emergent, nonreductionist concepts of evolution, vision science has to become comfortable accepting data and receiving guidance from human observers' conscious visual experience.
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http://dx.doi.org/10.1146/annurev-vision-111815-114655 | DOI Listing |
Front Neurol
January 2025
Department of Orthopaedics, China-Japan Union Hospital of Jilin University, Changchun, China.
Retinal ganglion cells (RGCs) generally fail to regenerate axons, resulting in irreversible vision loss after optic nerve injury. While many studies have shown that modulating specific genes can enhance RGCs survival and promote optic nerve regeneration, inducing long-distance axon regeneration through single-gene manipulation remains challenging. Nevertheless, combined multi-gene therapies have proven effective in significantly enhancing axonal regeneration.
View Article and Find Full Text PDFOphthalmol Sci
November 2024
Department of Ophthalmology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Objective: To explore the association between retinal microvascular parameters and glaucoma.
Design: Prospective study.
Subjects: The UK Biobank subjects with fundus images and without a history of glaucoma.
Br J Vis Impair
September 2024
The Laboratory for Visual Neuroplasticity, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, USA.
Cerebral visual impairment (CVI) is a brain-based visual disorder associated with injury and/or maldevelopment of central visual pathways. Visuospatial processing impairments are a cardinal feature of the complex clinical profile of individuals with CVI. Here, we assessed visuospatial processing abilities using a classic conjunction search task.
View Article and Find Full Text PDFLangmuir
January 2025
Center of Eco-Material and Green Chemistry, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China.
The adhesion of raindrops on car rearview mirrors poses a significant threat to traffic safety due to the resulting blurred vision. Transparent superhydrophobic coatings have emerged as a potential solution to this problem. However, the development of transparent superhydrophobic coatings is often hampered by complex preparation procedures, high costs, and limited substrate compatibility, rendering them unsuitable for practical applications.
View Article and Find Full Text PDFFood Res Int
February 2025
State Key Laboratory of Food Science and Technology, Jiangnan University, 214122 Wuxi, Jiangsu, China; Jiangsu Province International Joint Laboratory on Fresh Food Smart Processing and Quality Monitoring, Jiangnan University, 214122 Wuxi, Jiangsu, China.
The prepared foods sector has grown rapidly in recent years, driven by the fast pace of modern living and increasing consumer demand for convenience. Prepared foods are taking an increasingly important role in the modern catering industry due to their ease of storage, transportation, and operation. However, their processing faces several challenges, including labor shortages, inefficient sorting, inadequate cleaning, unsafe cutting processes, and a lack of industry standards.
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