AI Article Synopsis
- Postoperative nausea and vomiting (PONV) can lead to longer recovery times and lower patient satisfaction after surgery.
- Identifying risk factors and high-risk groups is crucial for effective management of PONV.
- Advances in medication have led to the use of combination therapies, showing better results when multiple antiemetic agents targeting different mechanisms are used together rather than a single medication.
Article Abstract
Postoperative nausea and vomiting (PONV) is associated with delayed recovery and dissatisfaction after surgical procedures. A key component to management is identifying risk factors and high-risk populations. Advances in pharmacologic therapeutics have resulted in agents targeting different pathways associated with the mediation of nausea and vomiting. This review focuses on these agents and the clinical aspects of their use in patients postoperatively. Combination therapies are reviewed, and studies demonstrate that when 2 or more antiemetic agents acting on different receptors are used, an overall improved efficacy is demonstrated when compared with a single agent alone in patients.
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| http://dx.doi.org/10.1016/j.anclin.2017.01.003 | DOI Listing |
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