Using the structural method of superimposition, childhood and adolescent rates of mandibular rotation and remodeling are described. The results pertain to a longitudinal sample of French-Canadian children, including 42 females with records at 6, 10, and 14 years of age and 39 males with records at 7, 11, and 15 years of age. There are no sex differences in rates of mandibular rotation and remodeling. Childhood rates of true rotation and angular remodeling are significantly greater than adolescent rates. Children whose first permanent molars had not erupted at the time of the first observation showed significantly greater rates of angular remodeling than children whose molars had already erupted. Over the eight year period, there were approximately 4.8 degrees of forward true rotation, between 5.2 and 6.4 degrees forward angular remodeling, and less than 1 degree of backward apparent rotation. During adolescence and the primary dentition stage, associations are strongest between true and apparent rotation. During the mixed dentition stage, true rotation is most closely correlated with angular remodeling. © 1992 Wiley-Liss, Inc.
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http://dx.doi.org/10.1002/ajhb.1310040514 | DOI Listing |
Arch Oral Biol
January 2025
Department of Prosthodontics and Periodontology, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil.
Objective: This longitudinal clinical study monitored annually the maxillary and mandibular bone remodeling and masticatory function in complete denture (CD) wearers rehabilitated with implant-retained mandibular overdentures (MO) over three years and combined radiographic and masticatory function data to assess the correlation between bone remodeling and masticatory function.
Design: Thirty-nine MO wearers were monitored annually to assess changes in: i) residual ridge in the anterior and posterior maxillary region; ii) posterior height and posterior area index (PAI) in the mandible; and iii) masticatory function. Bone remodeling was measured through linear and angular measurements using panoramic radiographs.
Commun Biol
December 2024
Institute for Biomedical Engineering and Institute of Pharmacology and Toxicology, Faculty of Medicine, University of Zurich, 8057, Zurich, Switzerland.
Proper oxygen delivery through the microvasculature to injury site is essential to ensure the metabolic cascade during wound healing. Adaptation of vascular structure and oxygenation is key to unravel the regulation of blood perfusion, oxygen distribution and new tissue formation. Yet, visualizing micrometabolic responses at large scale in unperturbed living tissue remains challenging.
View Article and Find Full Text PDFFront Physiol
October 2024
Department of Oral and Craniofacial Sciences, University of Missouri-Kansas City School of Dentistry, Kansas City, MO, United States.
Malocclusions are common craniofacial malformations that cause quality of life and health problems if left untreated. Unfortunately, the current treatment for severe skeletal malocclusion is invasive surgery. Developing improved therapeutic options requires a deeper understanding of the cellular mechanisms responsible for determining jaw bone length.
View Article and Find Full Text PDFBio Protoc
October 2024
IICB-Translational Research Unit of Excellence, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
The process of T-lymphocyte migration involves a complex interplay of chemical and mechanical signals. Mechanotransduction mechanisms in T lymphocytes enable them to efficiently navigate through diverse architectural and topographical features of the dynamic tissue macro- and micro-niches encountered during immune responses. Piezo1 mechanosensors are crucial for driving optimal T-cell migration by driving actin-cytoskeletal remodeling.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2024
State Key Laboratory of Extreme Photonics and Instrumentation, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Cytoskeleton remodeling which generates force and orchestrates signaling and trafficking to govern cell migration remains poorly understood, partly due to a lack of an investigation tool with high system flexibility, spatiotemporal resolution, and computational sensitivity. Herein, we developed a multimodal superresolution imaging system-based architecture-driven quantitative (ADQ) framework in spatiotemporal-angular hyperspace to enable both identification of the optimal imaging mode with well-balanced fidelity and phototoxicity and accurate postcharacterization of microtubule remodeling. In the ADQ framework, a pixel/voxel-wise metric reflecting heterogeneous intertubule alignment was proposed with improved sensitivity over previous efforts and further incorporated with temporal features to map dynamic microtubule rearrangements.
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