AI Article Synopsis
- The study investigated the effectiveness of adjunctive treatments, specifically low-level lasers, in enhancing the results of scaling and root planing (SRP) for patients with chronic periodontitis.
- The trial involved 80 gingival papilla biopsy samples from 60 patients, who were split into three treatment groups; some received just SRP, while others had SRP combined with laser therapy for varying durations.
- Results indicated that patients who received laser treatments alongside SRP showed a significant decrease in COX-2 expression in their gingival tissue, particularly those who had the most laser sessions (10 treatments).
Article Abstract
Adjunctive treatments to scaling and root planing (SRP) such as lasers, have been utilized in the treatment of chronic periodontitis, mainly aiming to suppress and eliminate the bacteria, as well as enhancing the healing response. Eighty gingival papilla biopsy samples were obtained from 60 patients diagnosed with chronic advanced periodontitis; randomly assigned to three treatment groups (n = 20), as well as 20 subjects with no periodontal disease [group A]. Group B received SRP on a single quadrant/day for four consecutive days. On day 5, all quadrants were rescaled. Groups C and D received the same treatment as group B plus laser application with the low-level diode laser (630-670 nm, 1.875 J/cm2) for five and ten consecutive days, respectively. Papilla biopsies were obtained from subjects and evaluated by RT-PCR for expression of COX-2. The values in the control group were 0.028 0.014 and baseline values for the examined groups were 0.16 0.18. Significantly decreased level of COX-2 expression for groups C and D was found after treatment, while lowest average expression was found in the group that had the 10 laser treatments supplemental to SRP (0,035 0,014). The results of this study show suppression of COX-2 in gingival tissue after low-level laser treatment as adjunct to SRP.
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| http://dx.doi.org/10.1007/s10103-017-2231-9 | DOI Listing |
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