Purpose: To determine the accuracy of VMAT treatment planning and delivery for patients undergoing radiotherapy in the head and neck.
Method And Materials: A dosimetric study of a typical head and neck treatment plan has been carried out using Chamber, film and TLD's placed inside an anthropomorphic phantom. Lateral and AP port films were taken to verify the isocenter prior to treatment. Multiple treatments were performed to assess the reproducibility and uncertainty in the TLD measurements. Gafchromatic film was used between the phantom slices and then analyzed as an independent check on the TLD results. The two data sets, from TLDs and films, were then compared with the treatment planning system dose calculations.
Results: The measured dose to the primary planning tumor volume agrees with the planning system within 2%. The comparison of the measured dose to the secondary tumor volume ranges from 3-6% and the spinal cord comparison ranges from 3-10%.
Conclusion: This new Smart Arc treatment, VMAT, has great benefits to the patient in that patient motion and internal motion of the tumor is dramatically reduced. Challenges arise in predicting the dose near heterogeneities between the treatment planning system and actual measurement.
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http://dx.doi.org/10.1118/1.4735478 | DOI Listing |
BMC Pregnancy Childbirth
January 2025
Department of Public Health Science, Indian Institute of Public Health Gandhinagar (IIPHG), Gandhinagar, Gujarat, India.
Background: Access to essential healthcare services is pertinent to the achievement of universal health coverage in any nation. The COVID-19 lockdown was used to mitigate the spread of the pandemic. Consequently, there was a reduction in the Utilisation of Basic Healthcare Services (UBHS) in diverse dimensions.
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January 2025
Department of Civil Engineering & Sustainable Structures, Technical University (Kadoorie), Jaffa Street, P.O. Box (7), Tulkarem, Palestine.
In the context of the Sustainable Development Goals (SDGs), which strive to ensure comprehensive access to fundamental water, sanitation, and hygiene (WASH) services, it is extremely imperative to prioritize communities in need and still disadvantaged. Moreover, tackling the worldwide sanitation crisis entails advancing the development of productive and sustainable sanitation systems and infrastructure. Sanitation planning is a multidimensional exercise encompassing multiple dimensions, stakeholders, and strategies, typically with conflicting objectives.
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January 2025
Longitudinal Studies Section, Translational Gerontology Branch, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA.
The neuromuscular junction shows several degenerative changes with aging, resulting in a reduction of transmission efficacy. These changes, paired with low-grade chronic inflammation, were considered triggers of the aging muscle processes. The main objective of this study is to assess the role of leukocyte count-derived ratios, nerve conduction velocity (NCV), and compound muscle action potential (CMAP) in determining time-dependent reduction in lower limb muscle explosive strength, a condition that has been defined as powerpenia.
View Article and Find Full Text PDFMol Neurobiol
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Research and Innovation Center, Shanghai Pudong Hospital, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Fudan University, Shanghai, 200433, China.
Investigating plasma proteomic signatures of dementia offers insights into its pathology, aids biomarker discovery, supports disease monitoring, and informs drug development. Here, we analyzed data from 48,367 UK Biobank participants with proteomic profiling. Using Cox and generalized linear models, we examined the longitudinal associations between proteomic signatures and dementia-related phenotypes.
View Article and Find Full Text PDFNurs Clin North Am
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UC Davis Health System, 4860 Y Street, Sacramento, CA 95817, USA. Electronic address:
Chronic wounds are a common condition that affects a patient's quality of life and drives the cost of health care delivery high. Vigilant wound assessment and close monitoring using adequate and reliable methods and technology are vital to wound care management. Wound assessment, including visual evaluation of tissue and surrounding skin, and measurements are essential in developing an appropriate care plan.
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