Purpose: To present EBT2 film verification of treatment planning with the eXtend System, a relocatable frame system for multiple-fraction or serial multiple-session radiosurgery.
Methods: A human head shaped phantom simulated the verification process for fractionated Gamma Knife (GK) treatment. Phantom preparation for eXtend Frame based treatment planning involved creating a dental impression, fitting the phantom to the frame system, acquiring a stereotactic computed tomography (CT) scan. A CT scan (Siemens, Emotion6) of the phantom was obtained with following parameters: Tube Voltage - 110 kV, Tube Current - 280 mA, pixel size - 0.5 mm × 0.5 mm and 1 mm slice thickness. A treatment plan with two 8 mm collimator shots and three sector blocking in each shot was made. Dose prescription of 4.0 Gy at 100% was delivered for the first fraction out of the two fractions planned. Gafchromic EBT2 film (ISP Wayne, NJ) was used as 2D verification dosimeter in this process. Films were cut and placed inside the film insert of the phantom for treatment dose delivery. Meanwhile a set of films from the same batch were exposed from 0 Gy to 12 Gy doses for calibration purpose. EPSON (Expression 10000XL) scanner was used for scanning the exposed films in transparency mode. Scanned films were analyzed with in-house made Matlab codes.
Results: Gamma index analysis of film measurement in comparison with TPS calculated dose resulted in high pass rates >90% for different tolerance criteria of 2%/2mm, 1%/1mm, and 0.5%/0.5mm. The isodose overlay and linear dose profiles of film measured and computed dose distribution on sagittal and coronal plane was in close agreement.
Conclusions: Through this study we propose a treatment verification QA method for eXtend frame based fractionated Gamma Knife radiosurgery using EBT2 film. Acknowledgement: Authors acknowledge the help of Andre Micke, ISP for sharing his expertise on EBT2 film.
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http://dx.doi.org/10.1118/1.4735487 | DOI Listing |
Sci Rep
November 2024
Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.
The sensitivity of radiochromic films to UV-blue light is increasingly considered for light dosimetry purposes, owing to their bidimensional detection capabilities and ease of use. While film response to radiation intensity has been widely investigated by commercial scanners, spatial resolution studies remain scarce, especially for small field-of-view applications. These are of growing interest due to the antimicrobial or photo-bio-stimulating effects of UV-blue light sources in in vitro, ex vivo and in vivo models, where precise knowledge of irradiation conditions with adequate spatial resolution is crucial.
View Article and Find Full Text PDFSci Rep
January 2024
Department of Physics, Faculty of Science, Zagazig University, PO 44519, Zagazig, Egypt.
The response of the modified GAFCHROMIC EBT2 radiochromic film to DC Oxygen glow discharge plasma was investigated using a flatbed scanner and an UV-Vis spectrophotometer. The film was modified by removing the polyester overlaminate, adhesive, and topcoat layers with a total thickness of 80 µm, and is now referred to as EBT2-M. The EBT2-M films were exposed to DC Oxygen plasma for different durations: 0, 0.
View Article and Find Full Text PDFRep Pract Oncol Radiother
May 2022
Department of Medical Physics, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Background: The presence of heterogeneity within the radiation field increases the challenges of small field dosimetry. In this study, the performance of MAGIC polymer gel was evaluated in the dosimetry of small fields beyond bone heterogeneity.
Materials And Methods: Circular field sizes of 5, 10, 20 and 30 mm were used and Polytetrafluoroethylene with density of 2.
PLoS One
August 2022
Medical Physics Department, Graduate School of Nuclear and Allied Sciences, University of Ghana, Atomic, Accra, Ghana.
Purpose: In vivo dosimetry is a quality assurance tool that provides post-treatment measurement of the absorbed dose as delivered to the patient. This dosimetry compares the prescribed and measured dose delivered to the target volume. In this study, a tissue-equivalent water phantom provided the simulation of the human environment.
View Article and Find Full Text PDFMed Phys
September 2022
Department of Medical Physics, University of the Free State, Bloemfontein, South Africa.
Background: This study measured and calculated dose distributions around a unique gold plaque for whole-eye radiotherapy (to treat retinoblastoma). The applicator consists of a pericorneal ring attached to the four extraocular muscles and four legs, each loaded with I-125 seeds. They are inserted beneath the conjunctiva in-between each pair of muscles and attached anteriorly to the ring.
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