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Anticoagulation in Patients With Device-Detected Atrial Fibrillation With and Without a Prior Stroke or Transient Ischemic Attack: The NOAH-AFNET 6 Trial.
J Am Heart Assoc
September 2024
Department of Cardiology University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf Hamburg Germany.
Background: Short and rare episodes of atrial fibrillation (AF) are commonly detected using implanted devices (device-detected AF) in patients with prior stroke or transient ischemic attack (TIA). The effectiveness and safety of oral anticoagulation in patients with prior stroke or TIA and device-detected AF but with no ECG-documented AF is unclear.
Methods And Results: This prespecified analysis of the NOAH-AFNET 6 (Non-Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial High Rate Episodes) trial with post hoc elements assessed the effect of oral anticoagulation in patients with device-detected AF with and without a prior stroke or TIA in the randomized, double-blind, double-dummy NOAH-AFNET 6 trial.
Oral anticoagulation in device-detected atrial fibrillation: effects of age, sex, cardiovascular comorbidities, and kidney function on outcomes in the NOAH-AFNET 6 trial.
Eur Heart J
May 2024
Department of Cardiology, University Heart & Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Wichterle hydron for breast augmentation - case reports and brief review.
Acta Chir Plast
March 2023
During the period of 1960s and 1970s, a new alloplastic material - Wichterle gel - was introduced in the field of plastic surgery. In 1961, a Czech scientist, prof. Otto Wichterle, had developed, along with his research team, a hydrophilic gel made of polymers, which fulfilled the high standards for prosthetic materials due to its hydrophilic, chemical, thermal and shape stability that provided a better tolerance in the body compared with other hydrophobic gels.
View Article and Find Full Text PDFA DOPA-functionalized chondroitin sulfate-based adhesive hydrogel as a promising multi-functional bioadhesive.
J Mater Chem B
March 2019
Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang Drive, N1.3-B2-13, Singapore 637457, Singapore.
Great progress has been achieved on the study of hydrogels, which were presented for the first time in 1960 by Otto Wichterle and Drahoslav Lím. The two crucial properties of hydrogels, namely high water content and biocompatibility, have made hydrogels ideal compositions in the development of bioadhesives in recent years. Chondroitin sulfate (CS), a sulfated glycosaminoglycan (GAG), is distributed throughout animal bodies, including cartilage and the extracellular matrix (ECM), and it has been widely utilized in the dietary supplement and pharmaceutical industries.
View Article and Find Full Text PDF[Otto Wichterle and Soft Contact Lenses].
Klin Monbl Augenheilkd
December 2018
Zentrum für Augenheilkunde, Universität zu Köln, Köln, Deutschland.
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