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Methodological Approaches to Comparative Trend Analyses: The Case of Adolescent Toothbrushing.
Int J Public Health
January 2025
Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Objectives: Research questions about how and why health trends differ between populations require decisions about data analytic procedure. The objective was to document and compare the information returned from stratified, fixed effect and random effect approaches to data modelling for two prototypical descriptive research questions about comparative trends in toothbrushing.
Methods: Data included five cycles of the Health Behaviour in School-aged Children 2006 to 2022, which provided a sample of 980192 11- to 15- year olds from 35 countries.
Exploring Inhibitory Control Processes in Highly Superior Autobiographical Memory (HSAM): A Single Case Study.
J Cogn
January 2025
Faculty of Medicine and Psychology, University of Sapienza, Rome, Italy.
Individuals who possess a Highly Superior Autobiographical Memory (HSAM) can remember their own lives in exceptional detail, retrieving specific autobiographical events in response to dates (e.g., 15 April 1995).
View Article and Find Full Text PDFOsteoporosis in axial radiographic spondyloarthritis: diagnostic limitations of bone mineral density and the need for comprehensive fracture risk assessment.
Reumatologia
December 2024
Clinical Department of Orthopedics and Traumatology, Jan Biziel University Hospital No. 2 in Bydgoszcz, Poland.
Axial radiographic spondyloarthritis (r-axSpA) is a chronic inflammatory joint disease that leads to a considerable decline in the quality of life of patients by impairment of function and mobility, which, in turn, brings about a deterioration of both physical and mental health. Osteoporosis (OP) is a significant issue in the course of r-axSpA. Fractures resulting from OP complicate the treatment of the underlying disease and reduce the quality of life of patients.
View Article and Find Full Text PDFThe future of siRNA-mediated approaches to treat von Willebrand disease.
Expert Rev Hematol
January 2025
Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Introduction: The clinical management of the inherited bleeding disorder von Willebrand disease (VWD) focuses on normalizing circulating levels of von Willebrand factor (VWF) and factor VIII (FVIII) to prevent or control bleeding events. The heterogeneous nature of VWD, however, complicates effective disease management and development of universal treatment guidelines.
Areas Covered: The current treatment modalities of VWD and their limitations are described and why this prompts the development of new treatment approaches.
Background: There is little evidence on the use or potential use of NHS repositories within the UK.
Methods: A mixed methods (quantitative/qualitative) study of two repositories: amber-the home of ambulance service research, and East Midlands Evidence Repository (EMER). A structured online questionnaire was distributed via the repository home page, and promoted via social media, email networks, and lists.
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