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Association of obesity with orbital fat expansion in thyroid eye disease.
BMC Ophthalmol
January 2025
Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, No. 138, Sheng Li Road, Tainan, 704, Taiwan.
Background: To investigate the association between obesity and orbital fat expansion in proptosis of thyroid eye disease.
Methods: This observational study retrospectively enrolled 87 participants who received orbital fat decompression surgery for thyroid eye disease. Primary outcome measures included average body mass index (BMI) and the proportion of the study sample with overweight and obesity, compared with the general Taiwanese population.
Surgical Timing for Patients with Thyroid Eye Disease Treated with Teprotumumab: A Collaborative Multicenter Study.
Ophthalmic Plast Reconstr Surg
December 2024
Department of Oculofacial Plastic Surgery, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
Purpose: To compare regression rates, characteristics, and surgical outcomes of thyroid eye disease patients who underwent orbit, strabismus, or eyelid surgery at various times during or after teprotumumab treatment.
Design: Multicenter, retrospective, observational cohort study.
Participants: Adult patients (age >18) with a minimum of 4 infusions of teprotumumab treatment for thyroid eye disease who had had eye surgery during or after treatment.
An Atypical Case of Orbital Wall Infarction Secondary to Sickle Cell Disease in an Adult and Review of Literature.
Ophthalmic Plast Reconstr Surg
December 2024
Moorfields Eye Hospital NHS Foundation Trust, Moorfields Eye Hospital, London, United Kingdom.
Sickle cell disease is known to cause painful vaso-occlusive crises in long bones with large marrows. Orbital infarction is a rare complication of sickle cell disease and usually presents in children and adolescents with acute onset periocular swelling mimicking orbital cellulitis. We describe an atypical case of a 38-year-old man with homozygous sickle cell disease who presented with isolated, complete ptosis of his OD with minimal swelling.
View Article and Find Full Text PDFMetastasizing dysgerminoma in an inland bearded dragon (Pogona vitticeps).
BMC Vet Res
December 2024
Clinical Unit for Diagnostic Imaging, University of Veterinary Medicine, Vienna, Austria.
Background: Malignant dysgerminomas are infrequently reported ovarian neoplasms in animals, especially in exotic pets (non-traditional companion animals [NTCAs]). In the few published case reports on reptilian species, examples are primarily postmortem without antemortem (clinical) assessment.
Patient Presentation: An adult, 13-year-old, spayed female inland bearded dragon (Pogona vitticeps) presented with lethargy, a right-sided head tilt, unilateral exophthalmos and ventrotemporal strabismus on the right eye.
Aggressive Synchronous Papillary and Likely Follicular Thyroid Carcinomas in a Patient with Graves' Disease.
J ASEAN Fed Endocr Soc
December 2024
Department of Endocrinology, Singapore General Hospital.
Article Synopsis
- - The case centers on a 67-year-old woman with both papillary and follicular thyroid carcinomas, initially diagnosed with thyrotoxicosis from Graves' disease, presenting with severe metastasis and invasive tumor growth.
- - Investigation revealed multiple metastases, including intra-cardiac tumor thrombus and bone fractures, leading to a diagnosis of synchronous thyroid cancer types, yet the patient chose palliative care over aggressive treatment options.
- - The case highlights the challenges in accurately diagnosing synchronous thyroid malignancies and the limitations of the ACR TI-RADS system in detecting certain ultrasonographic features that indicate cancer, especially in patients with Graves' disease.
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