The role and impact of cost-sharing mechanisms for prescription drug coverage.

CMAJ

School of Public Policy and Administration, Carleton University, Ottawa, Ont.

Published: May 2017

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433868PMC
http://dx.doi.org/10.1503/cmaj.170169DOI Listing

Publication Analysis

Top Keywords

role impact
4
impact cost-sharing
4
cost-sharing mechanisms
4
mechanisms prescription
4
prescription drug
4
drug coverage
4
role
1
cost-sharing
1
mechanisms
1
prescription
1

Similar Publications

The impact of mental health disorders on outcomes following total ankle arthroplasty: A systematic review.

Foot Ankle Surg

January 2025

Foot and Ankle Division, Department of Orthopaedic Surgery, NYU Langone Health, New York City, NY 10002, USA. Electronic address:

Background: The purpose of this systematic review was to evaluate the impact of mental health disorders (MHDs) on the clinical and functional outcomes following total ankle arthroplasty (TAA) for the treatment of end-stage ankle arthritis.

Methods: A systematic review of the EMBASE, MEDLINE, and Cochrane Library databases was conducted in April 2024 following PRISMA guidelines. Data collected included patient demographics, clinical outcomes, complications, and failures.

View Article and Find Full Text PDF

Multiomics in cancer biomarker discovery and cancer subtyping.

Adv Clin Chem

January 2025

School of Biosystem and Biomedical Science, College of Health Science, Korea University, Seoul, Republic of Korea; Department of Integrated Biomedical and Life Science, Korea University, Seoul, Republic of Korea; BK21FOUR R&E Center for Learning Health Systems, Korea University, Seoul, Republic of Korea; L-HOPE Program for Community-Based Total Learning Health Systems, Korea University, Seoul, Republic of Korea. Electronic address:

The advent of multiomics has ushered in a new era of cancer research characterized by integrated genomic, transcriptomic and proteomic analysis to unravel the complexities of cancer biology and facilitate the discovery of novel biomarkers. This chapter provides a comprehensive overview of the concept of multiomics, detailing the significant advances in the underlying technologies and their contributions to our understanding of cancer. It delves into the evolution of genomics and transcriptomics, breakthroughs in proteomics, and overarching progress in multiomic methodologies, highlighting their collective impact on cancer biomarker discovery.

View Article and Find Full Text PDF

Temporal dynamics of PM induced cell death: Emphasizing inflammation as key mediator in the late stages of prolonged myocardial toxicity.

Exp Cell Res

January 2025

Cardiovascular Center, College of Medicine, University of Cincinnati, Ohio-45267, United States of America; School of Chemical and Biotechnology, SASTRA Deemed University, Tirumalaisamudram, Thanjavur-613401, Tamil Nadu, India. Electronic address:

Multiple forms of cell death contribute significantly to cardiovascular pathologies, negatively impacting cardiac remodeling and leading to heart failure. While myocardial cell death has been associated with PM induced cardiotoxicity, the temporal dynamics of various cell death forms, such as apoptosis, ferroptosis, necroptosis, and pyroptosis, in relation to inflammatory processes, remain underexplored. This study examines the time-dependent onset and progression of these cell death pathways in the myocardium and their correlation with inflammation in a Wistar rat model.

View Article and Find Full Text PDF

This study utilizes single-cell RNA sequencing data to reveal the transcriptomic characteristics of breast cancer and normal epithelial cells. Nine significant cell populations were identified through stringent quality control and batch effect correction. Further classification of breast cancer epithelial cells based on the PAM50 method and clinical subtypes highlighted significant heterogeneity between triple-negative breast cancer (TNBC) and non-triple-negative breast cancer (NTNBC).

View Article and Find Full Text PDF

Shading stress promotes lignin biosynthesis in soybean seed coat and consequently extends seed longevity.

Int J Biol Macromol

January 2025

College of Life Science, Sichuan Agricultural University, Yaan, Sichuan 625014, China; Sichuan Engineering Research Center for Crop Strip Intercropping System, Key Laboratory of Crop Ecophysiology and Farming System in Southwest, Ministry of Agriculture, Chengdu, Sichuan 611130, China. Electronic address:

The macromolecular components of the seed coat, particularly lignin, play a critical role in regulating seed viability. In the maize-soybean intercropping (MSI) system, shading stress was reported to enhance the viability of soybean seeds. However, the specific role of seed coat lignin in this process remains poorly understood.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!