Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412159 | PMC |
http://dx.doi.org/10.4103/2347-5625.204498 | DOI Listing |
Cancers (Basel)
January 2025
Department of Thoracic Surgery, University of Rome La Sapienza, Sant'Andrea Hospital, 00189 Rome, Italy.
The landscape of surgical oncology is rapidly evolving with the advent of precision medicine, driven by breakthroughs in genomics and proteomics. This article explores how integrating molecular data is transforming surgical decision-making and enabling personalized treatment strategies. We examine emerging technologies such as next-generation sequencing, proteomic analysis, and molecular imaging, which provide critical insights into tumor biology and guide surgical interventions.
View Article and Find Full Text PDFNutrients
January 2025
Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Introduction: Nutritional care is a cornerstone of cancer treatment, with the potential to significantly improve patient outcomes by addressing malnutrition and enhancing recovery. Despite growing awareness, the integration of evidence-based nutritional strategies into oncology remains inconsistent. Following a 2020 survey that highlighted critical gaps, the NutriOnc Research Group launched targeted initiatives to raise awareness and improve practices.
View Article and Find Full Text PDFHum Immunol
January 2025
Department of Immunology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran. Electronic address:
Soluble immune checkpoints (sIC) are crucial factors in the immune system. They regulate immune responses by transforming intercellular signals via binding to their membrane-bound receptor or ligand. Moreover, soluble ICs are vital in immune regulation, cancer development, and prognosis.
View Article and Find Full Text PDFBiochem Pharmacol
January 2025
Institute of Pharmacology & Toxicology Zhejiang Province Key Laboratory of Anti-Cancer Drug Research College of Pharmaceutical Sciences Zhejiang University Hangzhou China; Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. Electronic address:
Breast cancer is one of the most common malignant tumors among women worldwide, and its high degree of metastasis significantly impacts treatment effectiveness leading to poor prognosis. The potential molecular mechanisms underlying breast cancer metastasis remain to be further elucidated. In this study, via database analysis, we revealed that the deubiquitinase josephin domain containing 2 (JOSD2) was abnormally amplified in patients with metastatic breast cancer, and was significantly negatively correlated with patient prognosis.
View Article and Find Full Text PDFMol Oncol
January 2025
Department of Oral Pathology, College of Dentistry, Gangneung-Wonju National University, Korea.
The dynamics of focal adhesions (FAs) are essential physiological processes involved in cell spreading, metastasis, and regulation of the actin cytoskeleton. FAs are complex structures comprising proteins, such as paxillin and zyxin, which interact with extracellular membranes and influence cell motility and morphology. Although related studies have been reported in various cancers, the function and molecular mechanisms of oral squamous cell carcinoma (OSCC) remain unknown.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!