AI Article Synopsis
- The study tested a new type of chamber that helps people breathe better when they're at high altitudes, like on Mount Kun Lun.
- Researchers watched rabbits and adult volunteers at different heights to see how the chamber affected their breathing and heart rates.
- Results showed that people and rabbits had better oxygen levels after using the chamber, but more testing is needed to see how well it works in real life.
Article Abstract
Objectives: To validate the effects of the new plateau hyperbaric chamber on alleviating high altitude hypoxia on Mount Kun Lun.
Methods: A prospective, controlled study of rabbits and adult volunteers was conducted at altitudes of 355, 2880 and 4532m. We obtained arterial blood samples from rabbits and volunteers before and after hyperbaric treatment. The respiratory rate, heart rate, and blood pressure (BP) of adult volunteers were monitored during hyperbaric treatment.
Results: The mean PaO levels of experimental group rabbits and volunteers increased significantly after 60min of hyperbaric treatment at 350, 2880 and 4532m. The mean PaCO and pH levels of rabbits were not significant different before and after hyperbaric treatment at each altitude. The mean PaCO and pH levels were not significant different at 355m in the human study. However, at 2880 and 4532m, pH fell with increasing PaCO levels in humans before and after hyperbaric treatment.
Conclusions: The new multiplace plateau hyperbaric chamber may be used to alleviate plateau hypoxia by increasing patient PaO. However, its value in treating AMS must be confirmed in field conditions.
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| http://dx.doi.org/10.1016/j.ajem.2017.04.034 | DOI Listing |
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