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Etanercept: A viable treatment option for young children with generalized pustular psoriasis.
Pediatr Investig
December 2024
The psychosocial impact of pediatric vitiligo, psoriasis, eczema, and alopecia: A systematic review.
Bull Menninger Clin
December 2024
Emergency medicine physician, NYC Health + Hospitals, Department of Emergency Medicine.
This review focuses on chronic pediatric skin conditions-vitiligo, psoriasis, alopecia, and eczema-and their profound psychosocial impact on children and adolescents. Currently, a comprehensive comparative analysis across these conditions is absent, and comparisons between diverse psychosocial measures are lacking. This review aims to bridge that gap through a systematic review analyzing studies from PubMed and Embase up to April 2023 according to PRISMA.
View Article and Find Full Text PDFBackground And Aims: Metformin is a widely used oral agent for controlling diabetes mellitus, but it also has other therapeutic benefits for various conditions. In addition, conventional oral metformin, and topical metformin have been used in, in-vitro studies in the treatment of acne, psoriasis, wound healing, and and so forth. While topical metformin has shown promising results in animal studies, there is limited data on its effectiveness in humans.
View Article and Find Full Text PDFComplicated iatrogenic Cushing's syndrome induced by topical clobetasol propionate in a child with psoriasis: a case report and review of the literature.
J Med Case Rep
December 2024
School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Long-term use of oral or parenteral corticosteroids is the most common cause of hypothalamic-pituitary-adrenal axis suppression and iatrogenic Cushing's syndrome. Still, iatrogenic Cushing's syndrome occurs rarely following the administration of topical corticosteroids.
Case Presentation: This case study discusses the misuse of a high-potency corticosteroid cream by an Iranian 5-year-old male with plaque-form psoriasis, resulting in Cushingoid symptoms including moon face, buffalo hump, red striae, and weight gain.
AIM2 deficiency in CD4 T cells promotes psoriasis-like inflammation by regulating Th17-Treg axis via AIM2-IKZF2 pathway.
J Autoimmun
December 2024
Department of Dermatology, the Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China; Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu, China. Electronic address:
Psoriasis vulgaris remains a common inflammatory skin disease globally. The imbalance between Th17 and Treg cells plays an integral role in the pathogenesis of psoriasis vulgaris, but the underlying mechanisms remain obscure. The role of AIM2 in Treg cell function in psoriasis is unclear.
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