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Impact of Expanded Eligibility for Veterans With Other Than Honorable Discharges on Treatment Courts and VA Mental Health Care.
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Mental Illness Research, Education, and Clinical Centers, Veterans Integrated Services Network 2, Bronx, New York.
Background: US Department of Veterans Affairs (VA) eligibility policies now allow comprehensive mental and behavioral health care services to be provided to veterans who received an Other Than Honorable (OTH) discharge upon separation from service. Research has shown a disproportionate mental health burden and elevated rates of criminal-legal involvement among these veterans. Eligibility policy shifts may impact programs and services designed to support veterans with criminal-legal involvement, such as veterans treatment courts.
View Article and Find Full Text PDFRevisiting the relationship between geopolitical risk and ecological footprint: A comprehensive analysis based on dual machine learning.
J Environ Manage
January 2025
School of Economics and Management, China University of Petroleum (East China), Qingdao, 266580, People's Republic of China. Electronic address:
Geopolitical conflicts and other risk events are subtly reshaping the global political and economic landscape, gradually disrupting the balance between economic development and ecological sustainability. Understanding the pathways through which geopolitical risks affect the ecological footprint is crucial for achieving ecological sustainability goals. This study employed dual machine learning models for high-precision analysis to deeply explore the intrinsic patterns of how geopolitical risks impact the ecological footprint.
View Article and Find Full Text PDFRevisiting phosphoregulation of Cdc25C during M-phase induction.
iScience
January 2025
Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Cdc25C undergoes a sudden and substantial gel mobility shift at M-phase onset, correlating with abrupt activation of both Cdc25C and Cdk1 activities. A positive feedback loop between Cdk1 and Cdc25C has been used to explain this hallmark phenomenon. Here, we demonstrate that the M-phase supershift and robust activation of Cdc25C are due to the site-comprehensive phosphorylation of its long intrinsically disordered regulatory domain without requiring Cdk1 or other major mitotic kinase activities.
View Article and Find Full Text PDFComprehensive phylogenetic analysis of newly detected rodent adenoviruses sheds light on ancient host-switches.
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HUN-REN Veterinary Medical Research Institute, H-1143 Budapest, Hungary.
Here we provide a comprehensive update on the diversity and genetic relatedness of adenoviruses occurring in rodents. Extensive PCR screenings revealed the presence of adenoviral DNA in samples originating from representatives of 17 rodent species from four different suborders of Rodentia. Distinct sequences of 28 different adenoviruses were obtained from the positive samples.
View Article and Find Full Text PDFA multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research.
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Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Recent developments in mass spectrometry-based proteomics have established it as a robust tool for system-wide analyses essential for pathophysiological research. While post-mortem samples are a critical source for these studies, our understanding of how body decomposition influences the proteome remains limited. Here, we have revisited published data and conducted a clinically relevant time-course experiment in mice, revealing organ-specific proteome regulation after death, with only a fraction of these changes linked to protein autolysis.
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