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Clinical presentations and complications of lichen sclerosus: A systematic review.
J Dtsch Dermatol Ges
December 2024
Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.
Lichen sclerosus (LS) is a chronic, inflammatory dermatosis most commonly characterized by changes in skin pigmentation and pruritus, with associated dyspareunia and genital architectural changes. There are a variety of complications associated with LS, which further worsen a patient's health-related quality of life. A systematic review was conducted to summarize the literature regarding clinical features of LS, as well as LS-associated complications.
View Article and Find Full Text PDFThe Influence of Genital Lichen Sclerosus on Sexual Health and Well-being: A Tripartite Comparative Analysis.
J Low Genit Tract Dis
January 2025
Dermatology Department, University of Brescia, ASST Spedali Civili di Brescia, Brescia, Italy.
Article Synopsis
- * The research involved 176 participants and used various questionnaires to evaluate sexual health, general health, and the severity of LS, revealing that LS leads to more significant sexual health issues than pemphigus or controls.
- * LS patients, particularly women, experienced greater difficulties with sexual function and increased psychological distress, highlighting the importance of effective management for those affected.
Role of surgical vaginoscopy through no-touch hysteroscope in the treatment of female reproductive polyps.
BMC Surg
December 2024
2Department of Obstetrics and Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Background: The study aims to investigate the application of surgical vaginoscopy via a no-touch hysteroscopic approach for the management of female genital polyps. The primary objective is to assess the feasibility of this technique in treating intrauterine pathologies in both pregnant and non-pregnant women.
Methods: A total of forty-six patients diagnosed with genital polyps underwent operative vaginoscopy at a university-affiliated hospital between April 1, 2017 and May 31, 2023.
Altieri modified Nesbit corporoplasty for the treatment of penile curvature: Comparison of local anesthesia vs loco-regional anesthesia on the clinical outcomes.
Arch Ital Urol Androl
October 2024
Department of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso.
Objective: To compare the safety profile and clinical outcomes of Altieri-modified Nesbit corporoplasty using two different anesthesia methods including spinal anesthesia and local anesthesia.
Materials And Methods: A total of 40 patients with congenital penile curvature (CPC) and Peyronie's disease (PD) underwent Altieri-modified Nesbit corporoplasty. Group 1 (n = 20) received spinal anesthesia, and Group 2 (n = 20) received local anesthesia.
Development of amphotericin B inclusion complex formulation in dissolvable microarray patches for intravaginal delivery.
Daru
December 2024
Faculty of Pharmacy, Hasanuddin University, Makassar, 90245, Indonesia.
Background: Amphotericin B (AMB) is a drug used to treat vulvovaginal candidiasis (VVC), which is a fungal infection affecting the vagina and vulva. Nevertheless, the substance's limited capacity to dissolve in water leads to poor absorption when taken orally, hence diminishing its therapeutic efficacy. In order to address this limitation, β-cyclodextrin (βCD) was used to create AMB in the form of an inclusion complex.
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