The required coagulant dosage is strongly related to the quality of raw water or wastewater. Online sensors for most quality parameters are now readily available to treatment facilities, yet remain rarely used in treatment process control. This paper presents the evaluation of an advanced coagulant dosing control system based on online measurements in full-scale processes. The popular multivariate analytical method, partial least square regression, was used to build up the relationship between the coagulant dose and wastewater quality. The system was tested in two wastewater treatment plants (WWTPs) in Norway. Coagulant savings up to 30% in Norwegian plants were observed with feed forward calibrations. The considerable savings reduce sludge production, leading to further cost saving on sludge treatment. This paper presents the method, function and experiences of the full-scale implementation of the system in different WWTPs.
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http://dx.doi.org/10.2166/wst.2017.058 | DOI Listing |
Pharmaceuticals (Basel)
November 2024
Independent Researcher, 5345 MT Oss, The Netherlands.
(1) Background: Danaparoid sodium is a heparinoid antithrombotic that has been used for over 40 years for prophylaxis of DVT in non-HIT patients and for the treatment of heparin-induced thrombocytopenia (HIT) with and without thrombosis. This update summarises current information on its pharmacology and reviews danaparoid dose management in a broad spectrum of clinical situations, including off-label indications. (2) Methods: Evidence from published clinical studies, case reports, compassionate use of danaparoid, and spontaneously reported serious adverse events is summarised and analysed by an interdisciplinary expert group to develop a consensus on dosing regimens of danaparoid for complex clinical situations, including vulnerable patient populations.
View Article and Find Full Text PDFMedicina (Kaunas)
December 2024
Department of Cardiovascular Surgery, University of Tsukuba Institute of Medicine, Tsukuba 305-8575, Japan.
: Vasopressin increases blood pressure through aquaporin-2-mediated water retention and is useful for managing hemodynamics after surgery. However, even after decades of study, clear clinical guidelines on doses and ideal use cases after cardiovascular surgery remain unclear. Here, the existing literature is synthesized on vasopressin use for cardiac surgeries and coupled with real-world clinical experience to outline a clearer clinical path for vasopressin use.
View Article and Find Full Text PDFCureus
December 2024
Obstetrics, Orlando Regional Medical Center, Orlando, USA.
Mymensingh Med J
January 2025
Dr Khondokar Shamim Shahriar Ziban Rushel, Assistant Professor, Department of Cardiac Surgery, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh; E-mail:
Heparin is an anticoagulant used invariably in all cardiac surgery. Heparin dosing and its reversal were determined by monitoring activated clotting time (ACT). Intermittent heparin dosing after initial bolus dose is widely practiced to maintain ACT level 200-300 seconds in Off-pump coronary artery bypass surgery (OPCAB).
View Article and Find Full Text PDFBMC Musculoskelet Disord
December 2024
Shanxi Bethune Hospital, Third Hospital of Shanxi Medical University, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Background: This study aims to evaluate the optimal dose of intravenous tranexamic acid (TXA) for reducing blood loss in spinal surgery.
Methods: A systematic search was conducted in the PubMed, Embase, Cochrane Library database from inception until November 2023. Randomized controlled trials (RCTs) incorporating diverse TXA dosing regimens for spinal surgery were included.
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