It is believed that nanoemulsions were emerged as a promising candidate to improve the qualities of natural essential oil towards antimicrobial and insecticidal applications. In the present study, we have focused on the encapsulation of Vitex negundo L. leaf essential oil using Polysorbate80 for its different biological activities including antioxidant, bactericidal and larvicidal activity against dengue fever vector Aedes aegypti L. Initially, the nanoemulsion was prepared by low energy method and droplet size of the formulated nanoemulsion was characterized by using Dynamic Light Scattering analysis. The freshly prepared V. negundo essential nanoemulsion was observed with the mean droplet size of below 200 nm indicating its excellent stability. Further, the larvicidal activity of essential oil and nanoemulsion with various concentrations (25, 50, 100, 200 and 400 ppm). The larvicidal activities were tested 2nd and 3rd instar larval mortality rate that was observed against the 12 and 24 h exposure period. After a 12 h exposure period, the larvicidal activities of 2nd instar larva were observed as essential oil (73.33 ± 1.88), nanoemulsion (81.00 ± 0.88) and the larvicidal activities of 3rd instar larva were displayed essential oil (70.33 ± 2.60) and nanoemulsion (79.00 ± 3.70). Likewise, after a 24 h exposure period, the larvicidal activities of 2nd instar larva were observed as essential oil (90.30 ± 2.15), nanoemulsion (94.33 ± 1.20) and the larvicidal activities of 3rd instar larva were essential oil (80.66 ± 0.66) and nanoemulsion (93.00 ± 1.25) respectively. We finally concluded that the developed plant-based emulsion essential oil systems were thermodynamically stable. Owing to its improved bioavailability and biocompatibility, formulated nanoemulsion can be used in various biomedical applications including drug delivery as well as disease transmitting mosquito vector control. Graphical abstract ᅟ.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11356-017-9118-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Exploring the potential anticancer targets and mechanistic pathways of essential oil based on network pharmacology.
J Asian Nat Prod Res
January 2025
School of Life Sciences, Sichuan Normal University, Chengdu 610101, China.
This study aimed to assess the composition of essential oil (EBE) and identify potential targets for inhibiting human hepatocellular carcinoma cell proliferation. The plants were collected from four regions: Jiuzhi, Qinghai; Ruoergai, Sichuan; Aba, Sichuan; and Jiulong, Sichuan. Four EBEs (named No.
View Article and Find Full Text PDFAn Assessment of the Cyto-Genotoxicity Effects of Green-Synthesized Silver Nanoparticles and ATCBRA Insecticide on the Root System of .
Nanomaterials (Basel)
January 2025
King Abdullah Institute for Nanotechnology, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
We aimed to synthesize silver nanoparticles (AgNPs) using (cardamom) extracts and assess the cytotoxicity and genotoxicity of the cardamom extract, -AgNPs, and the insecticide ATCBRA-commonly used for pest control-on the root system of (broad bean). The chemical composition of the aqueous cardamom extract was identified and quantified using GC-MS, revealing a variety of bioactive compounds also present in cardamom essential oil. These included α-terpinyl acetate (21.
View Article and Find Full Text PDFPreparation of Zwitterionic Sulfobetaines and Study of Their Thermal Properties and Nanostructured Self-Assembling Features.
Nanomaterials (Basel)
January 2025
Renewable Energy Laboratory, National Laboratory Astana, Nazarbayev University, Astana 010000, Kazakhstan.
Zwitterionic polymers have garnered significant attention for their distinctive properties, such as biocompatibility, antifouling capabilities, and resistance to protein adsorption, making them promising candidates for a wide range of applications, including drug delivery, oil production inhibitors, and water purification membranes. This study reports the synthesis and characterization of zwitterionic monomers and polymers through the modification of linear, vinyl, and aromatic heterocyclic functional groups via reaction with 1,3-propanesultone. Four zwitterionic polymers with varying molecular structures-ranging from linear to five and six membered ring systems-were synthesized: poly(sulfobetaine methacrylamide) (pSBMAm), poly(sulfobetaine-1-vinylimidazole) (pSB1VI), poly(sulfobetaine-2-vinylpyridine) (pSB2VP), and poly(sulfobetaine-4-vinylpyridine) (pSB4VP).
View Article and Find Full Text PDFSurface Modifications and Antifungal Efficacy of Origanum Oil Incorporation in Denture-based Materials: An Study.
J Contemp Dent Pract
September 2024
Graduate Program in Dentistry, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil; Department of Dentistry, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands, ORCID: https://orcid.org/0000-0002-5166-8233.
Aim: This study aimed to assess if the addition of origanum oil to denture materials could decrease microorganisms counts and biofilm formation without changing their mechanical/surface properties.
Materials And Methods: A total of 66 resilient denture liner discs (SoftConfort, Dencril Comércio de Plásticos Ltda, SP, Brazil) were prepared with fixed dimensions of 10 × 3 mm for biofilm assay ( = 36) and 12 × 2 mm for sorption-solubility tests ( = 30) containing three oil concentrations - 0, 2.5 and 5%, thereby = 12 per each group samples for biofilm assay and = 10 per each group for sorption-solubility test respectively.
Putative effects of moringa oil or its nano-emulsion on the growth, physiological responses, blood health, semen quality, and the sperm antioxidant-related genes in ram.
BMC Vet Res
January 2025
Department of Animal Production, Faculty of Agriculture, Mansoura University, Mansoura, 35516, Egypt.
Phytochemicals have been effectively used to enhance the growth and productivity of farm animals, while the potential roles of essential oils and their nano-emulsions are limited. This plan was proposed to investigate the impacts of orally administered moringa oil (MO) or its nano-emulsion (NMO) on the growth, physiological response, blood health, semen attributes, and sperm antioxidant-related genes in rams. A total of 15 growing Rahmani rams were enrolled in this study and allotted into three groups.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!