The case of an 89-year-old man who was referred for a painless decrease of vision in his right eye (RE) is reported. Fundus examination of the RE showed an elevated amelanotic lesion located in the posterior pole with an adjacent focal round pigmented lesion. There was also a more peripheral amelanotic lesion extending from 6 to 9 o'clock clockwise inferotemporally. Uveitis workup and imaging studies of brain and orbits were normal. A retinochoroidal biopsy was done and showed the presence of choroidal extranodal marginal zone lymphoma. The patient was treated with external beam radiotherapy. This report presents a review of the literature of all reported cases of choroidal extranodal marginal zone lymphoma.
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http://dx.doi.org/10.2147/IMCRJ.S129171 | DOI Listing |
Eye (Lond)
October 2024
Ocular Oncology Service, Royal Hallamshire Hospital, Sheffield, UK.
Background: Differentiating neoplastic and non-neoplastic uveal tumours can present a diagnostic challenge; intra-ocular biopsy may be necessary. The novel trans-scleral Essen Forceps biopsy (TSEB) technique can improve diagnostic yield compared to fine needle aspiration biopsy (FNAB). We present a case demonstrating the technique and its added value.
View Article and Find Full Text PDFRetin Cases Brief Rep
January 2025
Vitreoretinal Department, Moorfields Eye Hospital, London, United Kingdom.
Purpose: To present an orbital extranodal marginal zone B-cell lymphoma (mucosa-associated lymphoid tissue lymphoma) with increased choroidal thickness as the first diagnostic sign.
Methods: A patient presented with mild blurred vision in the left eye. Progressively increased choroidal thickness was demonstrated by enhanced depth imaging-optical coherence tomography and ocular ultrasound-confirmed diffuse choroidal effusion.
Oncol Lett
September 2023
Department of Medicine and Surgery, Unicamillus, Saint Camillus International University of Health Sciences, International Medical University in Rome, I-00131 Rome, Italy.
Primary central nervous system (CNS) extranodal marginal zone B-cell lymphoma (MZBL) is a rare low-grade non-Hodgkin lymphoma, characterised predominantly by small B cells, plasma cells, monocytoid cells and scattered large immunoblasts. Primary CNS MZBL is a slow-growing tumour that remains localised and is characterised by an excellent clinical prognosis. The present study describes the case of a 48-year-old HIV-negative female patient with a history of head trauma 1 year prior, who presented with worsening neurological symptoms and a magnetic resonance imaging finding of a ~3-cm extra-axial mass within the left lateral ventricle.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
August 2023
Department of Ophthalmology, Eye, Ear, Nose and Throat Hospital, Shanghai Medical School, Fudan University, Shanghai, 200031, China.
Purpose: To investigate the ultrasonographic features in patients with primary uveal mucosa-associated lymphoid tissue (MALT) lymphoma.
Methods: Medical records of 12 patients (13 eyes) diagnosed with primary uveal MALT lymphoma between September 2014 and September 2021 were retrospectively reviewed. Ultrasonography, B-scan ultrasonography, color Doppler flow imaging, and ultrasound biomicroscopy findings were retrieved from the medical records.
Ocul Immunol Inflamm
August 2024
Department of Ophthalmology, Virgen Del Rocío University Hospital, Seville, Spain.
Purpose: To describe the ophthalmic findings and diagnosis of a case of intravascular large B-cell lymphoma.
Methods: Clinical case observational report.
Clinical Case: A Spanish 51-year-old man referred to our hospital with a diagnosis of panuveitis.
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