HIV Latency Gets a New Histone Mark. | LitMetric

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HIV Latency Gets a New Histone Mark. | LitMetric

HIV Latency Gets a New Histone Mark.

Bryan C Nikolai Qin Feng

Cell Host Microbe

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

Published: May 2017

Transcriptional latency of integrated HIV-1 provirus represents a major obstacle to curing HIV. In this issue of Cell Host & Microbe, Boehm et al. (2017) identify a new lysine methyltransferase that writes a repressive histone mark associated with HIV-1 latency. The results are important for strategies to pharmacologically reverse HIV-1 latency.

Download full-text PDF	Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484844	PMC
http://dx.doi.org/10.1016/j.chom.2017.04.012	DOI Listing

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