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http://dx.doi.org/10.1016/j.ijwd.2015.09.001 | DOI Listing |
J Invest Dermatol
May 2024
B.A.I. Biosciences, Cambridge, Massachusetts, USA.
J Invest Dermatol
February 2024
Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. Electronic address:
J Invest Dermatol
August 2023
Department of Dermatology, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:
Over the past 70 years, sunscreens have evolved from beach products designed to prevent sunburn to more cosmetically elegant skincare products intended to protect against multiple long-term adverse consequences of characteristically low-intensity daily UV and visible light exposure. Sunscreen testing and labeling intended to quantify such protection are unfortunately often misunderstood by users and have also led to illegal misleading and potentially dangerous industry practices. Changes in regulatory requirements, better policing, and more informative sunscreen labeling would benefit users and their physician advisors.
View Article and Find Full Text PDFClin Pharmacol Drug Dev
October 2021
Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.
J Invest Dermatol
April 2021
Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:
This Perspective briefly reviews the relationship between UV-induced mutations in habitually sun-exposed human skin and subsequent development of actinic keratoses (AKs) and skin cancers. It argues that field therapy rather than AK-selective therapy is the more logical approach to cancer prevention and hypothesizes that treatment early in the process of field cancerization, even prior to the appearance of AKs, may be more effective in preventing cancer as well as more beneficial for and better tolerated by at-risk individuals. Finally, the Perspective encourages use of rapidly advancing DNA analysis techniques to quantify mutational burden in sun-damaged skin and its reduction by various therapies.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!