AI Article Synopsis
- Two cats experienced exercise intolerance and breathing difficulties due to a rare condition called unilateral absence of the right pulmonary artery, identified through computed tomography angiography (CTA).
- One cat developed severe pulmonary hypertension and ultimately had to be euthanized despite treatment, while the other cat managed well for over four years with medication and showed no signs of pulmonary hypertension.
- The study highlights the importance of CTA in diagnosing congenital heart malformations and suggests that severe pulmonary hypertension negatively impacts prognosis in affected cats.
Article Abstract
Case Series Summary: Two cats were evaluated for progressive exercise intolerance, dyspnea and unilateral infiltrate of the left lung. Computed tomography angiography (CTA) revealed absence of the right pulmonary artery in both cats with systemic arterial collateral vessels perfusing the right segmental pulmonary arteries. In one case, the collateral vessels arose from the esophageal artery, while in the other case they derived off the right costocervical trunk. One cat was diagnosed with pulmonary hypertension and was euthanized owing to progressive respiratory distress despite medical management with sildenafil, pimobendan, clopidogrel and furosemide. The other cat, without echocardiographic evidence of pulmonary hypertension, was successfully managed with furosemide and enalapril for more than 4 years.
Relevance And Novel Information: CTA allowed visualization of a rare congenital heart malformation, unilateral absence of the right pulmonary artery, in two cats and accurately characterized the source of collateral blood supply to the affected lung. Severe pulmonary hypertension may be a negative prognostic factor in cats with this condition as medical therapy in the cat without evidence of pulmonary hypertension resolved clinical signs, while the cat with severe pulmonary hypertension died from the disease.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362921 | PMC |
| http://dx.doi.org/10.1177/2055116916671480 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[The image is the key: unilateral absence of a branch of the pulmonary artery].
Andes Pediatr
August 2023
Departamento de Pediatría, Hospital Clínico Universitario San Cecilio, Granada, España.
Unlabelled: Unilateral absence of pulmonary artery (UAPA) is a rare and underdiagnosed entity. Due to its varied clinical expression, especially respiratory and most frequently associated with congenital heart disease, it can also present in isolation and remain asymptomatic for a long time. There is no consensus on its treatment, which is generally reserved for the presence of complications, mainly pulmonary hypertension, hemoptysis, or recurrent respiratory infections.
View Article and Find Full Text PDFPulmonary arterial hypertension-induced occlusion of left main coronary artery: pulmonary artery reconstruction surgery resolves stenosis indirectly.
J Invasive Cardiol
January 2025
Department of Echocardiography, Wuhan Asia Heart Hospital Affiliated to Wuhan University of Science and Technology. No.753 Jinghan Road, Hankou District, Wuhan, China. Email:
The burden of illness of the organ manifestations of systemic sclerosis: a pragmatic, targeted review.
Clin Exp Rheumatol
January 2025
Department of Medicine, Division of Rheumatology, University of California, Los Angeles, USA.
Objectives: This structured, targeted literature review aimed to assess the mortality, humanistic and economic burden of eight organ manifestations which are commonly experienced by systemic sclerosis patients.
Methods: Identification of relevant literature was carried out by searching in Ovid MEDLINE and EMBASE, PubMed, and NHS Economic Evaluation Database in August 2023. Studies reporting original data on patients with systemic sclerosis with at least one of eight organ manifestations (interstitial lung disease and/or pulmonary hypertension, skin, peripheral vascular, musculoskeletal, gastrointestinal, cardiac or renal involvement) published within the last 15 years were included.
Mortality Prediction in Newborns With Persistent Pulmonary Hypertension: A Comparison of Four Illness Severity Scores.
Pediatr Pulmonol
January 2025
Department of Pediatrics, Division of Neonatology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
Objective: This study aimed to compare the accuracy of four neonatal illness severity scores for predicting mortality in persistent pulmonary hypertension of the newborn (PPHN).
Study Design: This retrospective study included neonates diagnosed with PPHN between 2013 and 2022. The illness severity scores of four commonly used tools were completed for each infant: the Clinical Risk Index for Babies-II (CRIB-II), the Score for Neonatal Acute Physiology-Perinatal Extension version II (SNAPPE-II) in the first 12 h after admission and maximum oxygenation index (OI) and Vasoactive-Inotropic score (VIS) during the first 24 h (OI24max and VIS24max), 48 h (OI48max and VIS48max), and 72 h (OI72max and VIS72max) after admission.
[A case of transcatheter membrane-covered stent shunt for severe pulmonary hypertension post-CHD surgery].
Zhonghua Xin Xue Guan Bing Za Zhi
January 2025
Department of Cardio-Thoracic Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai200127, China.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!