Background: This study evaluated whether family history of depression predicts major depression in midlife women above and beyond static risk factors (such as personal history of depression prior to midlife) and risks that may change dynamically across midlife (such as menopausal, psychosocial, and health profiles).
Methods: Participants were 303 African American and Caucasian women (42-52 years at baseline) recruited into the Study of Women's Health across the Nation (SWAN) Mental Health Study (MHS) in Pittsburgh. Major depression was assessed annually with Structured Clinical Interviews for DSM-IV. Family mental health history was collected at the ninth or tenth annual follow-up. Random effects logistic regression was used to assess the relationship between family history of depression and midlife depression, controlling for baseline sociodemographic characteristics and time-varying risk factors.
Results: Family history of depression was associated with midlife depression after adjusting for participant's history of major depression prior to midlife, trait anxiety and baseline age, and time-varying menopausal status, body mass index, very upsetting life events, and chronic difficulties (OR = 2.24, 95% CI = 1.17-4.29, P = .02). Higher odds of major depression were found when women were late perimenopausal or postmenopausal relative to when they were premenopausal or early perimenopausal (OR = 3.01, 95% CI = 1.76-5.15, P < .0001). However, menopausal status was only associated with major depression among women without a family history.
Conclusions: Family history of depression predicts major depression in midlife women independent of the menopausal transition and other time-varying covariates. Notably, the menopausal transition was associated with increased risk only among women without a family history of depression.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585035 | PMC |
| http://dx.doi.org/10.1002/da.22651 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Depression risk among breast cancer survivors: a nationwide cohort study in South Korea.
Breast Cancer Res
December 2024
Department of Clinical Research Design and Evaluation, The Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Background: Depression among breast cancer survivors is a significant concern affecting their long-term survivorship and quality of life. This study investigates the incidence of depression among breast cancer survivors and identifies associated risk factors.
Methods: This retrospective cohort study used data from the Korean National Health Insurance Service database and included 59,340 breast cancer patients without a history of depression who underwent surgery between January 1, 2010, and December 31, 2016.
Prevalence and associated factors of psychiatric problems in children aged 6-18 years with type-1 diabetes mellitus in Gondar, Ethiopia: a cross-sectional study.
BMC Endocr Disord
December 2024
Departemnt of Pediatrics and Child Health, School of Medicine, University of Gondar, Gondar, Ethiopia.
Background: Diabetes mellitus is one of the most common chronic illnesses in children with multiple psychosocial, economic and developmental effects. Psychiatric disorders such as depression, anxiety, psychological distress, and eating disorders are more common in diabetic patients than the non-diabetic once. The main objective of our study was to assess Prevalence and associated factors of psychiatric problems in children aged 6-18 years with type 1 diabetes mellitus in Gondar, Ethiopia.
View Article and Find Full Text PDFFalls in Persons with Cognitive Impairment-Incidence and Characteristics of the Fallers.
Geriatrics (Basel)
December 2024
The Norwegian National Center for Aging and Health, Vestfold Hospital Trust, N-3103 Tønsberg, Norway.
The annual incidence of falls is high in older adults with impaired cognitive function and dementia, and injuries have a detrimental effect on disability-adjusted life-years and public health spending. In this registry-based study, fall incidence and characteristics of the fallers were explored in a large population with cognitive impairment. : NorCog, "The Norwegian Registry of Persons Assessed for Cognitive Symptoms", is a national research and quality registry with a biomaterial collection.
View Article and Find Full Text PDFNurses' Clinical Practice in Nursing Homes: Depressive Symptoms and Fall Risk Assessment.
Geriatrics (Basel)
December 2024
School of Nursing Sciences, University of Applied Sciences and Arts Western Switzerland, 1950 Sion, Switzerland.
Background: Depression and falls are highly prevalent, interrelated concerns for nursing home (NH) residents. Relationships between depression and falls should guide nurses towards developing evidence-based practices for assessing these conditions together. This study aimed to ascertain NH nurses' clinical practices and perceptions regarding the assessment of depression and fall risk.
View Article and Find Full Text PDFLong-term Effects of Local Area New Deal Work Relief in Childhood on Late Life Depression.
J Gerontol B Psychol Sci Soc Sci
December 2024
Department of Epidemiology and Population Health, Stanford University, Stanford, CA, USA.
Objective: To investigate whether childhood exposure to local area New Deal emergency employment work relief activity was associated with lower depressive symptoms in late life.
Methods: This study utilized individual-level data from the Wisconsin Longitudinal Study (WLS) linked to the full count 1940 census. New Deal emergency employment programs were the largest non-wartime expansion in government led infrastructure, services, and employment policy in U.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!